# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA747018 | F | Proteolytic properties against human muscle type nicotinic Acetylcholine receptor (nAchr) from TE671 cells, expressed as acidity constant (pKa1) | 2 | cell-based format | Scientific Literature | |||
2. | ALA747019 | F | Proteolytic properties against human muscle type nicotinic Acetylcholine receptor(nAchr) from TE671 cells, expressed as acidity constant (pKa1) | 4 | cell-based format | Scientific Literature | |||
3. | ALA841621 | F | Proteolytic properties against human muscle type nicotinic Acetylcholine receptor(nAchr) from TE671 cells, expressed as acidity constant (pKa2) | 6 | cell-based format | Scientific Literature | |||
4. | ALA841622 | F | Proteolytic properties against human muscle type nicotinic Acetylcholine receptor(nAchr) from TE671 cells, expressed as acidity constant (pKa3) | 4 | cell-based format | Scientific Literature | |||
5. | ALA842920 | F | Tested for functional activity against alpha-1 neuronal nicotinic acetylcholine receptor(nAChR) expressed in TE671 cells using isotopic rubidium efflux assay. | 4 | cell-based format | Scientific Literature | |||
6. | ALA842921 | F | Tested for functional activity against neuronal nicotinic acetylcholine receptor(nAChR) expressed in K177 cells using isotopic rubidium efflux assay. | 1 | cell-based format | Scientific Literature | |||
7. | ALA842922 | F | Percent intrinsic activity against K177 cells relative to 100 uM (S)-nicotine. | 1 | cell-based format | Scientific Literature | |||
8. | ALA842923 | F | Percent intrinsic activity against TE671 cells relative to 100 uM (S)-nicotine. | 4 | cell-based format | Scientific Literature | |||
9. | ALA2024823 | F | Antagonist activity at alpha1 nAChR | 1 | assay format | Scientific Literature | |||
10. | ALA2026878 | F | Antagonist activity at alpha1 nAChR | 1 | assay format | Scientific Literature | |||
11. | ALA1031429 | B | Displacement of bungarotoxin from human nAChR alpha1 receptor at 3 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA1036699 | F | Agonist activity to alpha-1-beta-1-epsilon-delta nAChR expressed in Xenopus oocytes assessed as response current at 100 uM by two-electrode voltage clamp relative to acetylcholine | 4 | cell-based format | Scientific Literature | |||
13. | ALA1212433 | F | Antagonist activity at human alpha1 nAChR in human TE671 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA1828495 | B | Binding affinity to alpha1 nAchR expressed in human TE671 cells | 9 | cell-based format | Scientific Literature | |||
15. | ALA1839763 | B | Binding affinity to human bungrotoxin binding site of nicotinic acetylcholine receptor alpha1 at 10 uM by radioligand binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA2445501 | B | Displacement of [125I]-alpha-Bungarotoxin from nicotinic acetylcholine alpha1 receptor bungarotoxin binding site in human RD cells at 10 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA3076137 | B | Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta1 nicotinic acetylcholine receptor at >300 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA3076138 | B | Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta1 nicotinic acetylcholine receptor subunits | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
19. | ALA2329941 | F | Antagonist activity at nAChR alpha1 (unknown origin) by [35S]GTPgammaS binding assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
20. | ALA2396242 | B | Inhibition of human nicotinic acetylcholine alpha1 receptor bungarotoxin binding site at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |