# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3242678 | B | Inhibition of mouse hippocampal neurons ASIC1a transfected in CHO cells assessed as reduction of acid-evoked current at 3 uM at -60 mV holding potential by two-electrode voltage-clamp electrophysiology assay | Mus musculus | 1 | ALA3232957 | cell-based format | Scientific Literature | |
2. | ALA3242679 | B | Inhibition of mouse hippocampal neurons ASIC1b transfected in CHO cells assessed as reduction of acid-evoked current at 3 uM at -60 mV holding potential by two-electrode voltage-clamp electrophysiology assay | Mus musculus | 1 | ALA3232957 | cell-based format | Scientific Literature | |
3. | ALA4031278 | B | Inhibition of mouse ASIC1a receptor E425C mutant expressed in xenopus lavies oocytes assessed as inhibition of channel current up to 1 mM at pH 7.4 by voltage clamp method | Mus musculus | 1 | ALA4028862 | cell-based format | Scientific Literature | |
4. | ALA4031279 | B | Inhibition of mouse ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of channel current up to 1 mM at pH 7.4 by voltage clamp method | Mus musculus | 1 | ALA4028862 | cell-based format | Scientific Literature | |
5. | ALA4340214 | B | Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | Mus musculus | 25 | ALA4339228 | cell-based format | Scientific Literature | |
6. | ALA5227707 | B | Inhibition of mouse ASIC1a expressed in genetically engineered-CHO-K1 cells at 10 uM preincubated for 10 mins at pH 7.4 followed by cell stimulation with proton injection at pH 6.5 by electro-chromic fluorescence voltage sensor-based assay relative to control | Mus musculus | 12 | ALA5226310 | cell-based format | Scientific Literature |