| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5256717 | B | Agonist activity at human GPR52 expressed in HEK293F assessed as cAMP accumulation preincubated for 30 mins followed by cAMP detection reagent and measured after 1 hr by HTRF analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 2. | ALA3367421 | B | Agonist activity at GPR52 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 3. | ALA3367422 | B | Agonist activity at GPR52 (unknown origin) relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA3367423 | F | Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay relative to N-(2-Hydroxyethyl)-3-{2-[3-(trifluoromethyl)benzyl]-1-benzofuran-4-yl}benzamide | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA3367424 | F | Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 6. | ALA3367439 | F | Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production at 10 uM after 30 mins by Alphascreen assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4034862 | F | Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 8. | ALA4034863 | F | Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay relative to (N-(2-hydroxyethyl)-3-(2-(3-(trifluoromethyl)benzyl)-1-benzofuran-4-yl)benzamide) | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 9. | ALA4034897 | F | Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level at 1 uM after 30 mins by AlphaScreen assay relative to (N-(2-hydroxyethyl)-3-(2-(3-(trifluoromethyl)benzyl)-1-benzofuran-4-yl)benzamide) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4221329 | F | Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 11. | ALA4221342 | F | Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay relative to N-(2-hydroxyethyl)-3-[2-[3-(trifluoromethyl)benzyl]-1-benzofuran-4-yl]benzamide | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 12. | ALA4705673 | F | Agonist activity at human GPR52 expressed in HEK293 cells assessed as increase in cAMP levels incubated for 15 mins by Glosensor cAMP assay relative to N-(2-hydroxyethyl)-1-(4-(3-(trifluoromethyl)benzyl)pyridin-2-yl)indoline-4-carboxamide | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 13. | ALA4705674 | F | Agonist activity at human GPR52 expressed in HEK293 cells assessed as increase in cAMP levels incubated for 15 mins by Glosensor cAMP assay | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 14. | ALA4711941 | F | Antagonist activity at GPR52 (unknown origin) expressed in HEK293 cells assessed as inhibition of WO459-induced cAMP accumulation preincubated for 15 mins followed by WO459 addition and measured after 30 mins by LANCE Ultra cAMP kit based microplate reader analysis | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 15. | ALA4806971 | F | Agonist activity at GPR52 (unknown origin) expressed in CHO-K1 or HEK293 cells assessed as intracellular cAMP accumulation incubated for 1 hr by HTRF assay | Homo sapiens | 208 | cell-based format | Patent Bioactivity Data | ||
| 16. | ALA4883190 | F | CHO-based cAMP assay (human) | Homo sapiens | 2 | assay format | Donated Chemical Probes - SGC Frankfurt | ||
| 17. | ALA4883456 | B | PRESTO-Tango GPCRome screening (GPR52) | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | |||
| 18. | ALA5210074 | F | Affinity Phenotypic Cellular interaction (Alphascreen (cAMP increase in human GPR52 expressed CHO cell line)) EUB0000317b GPR52 | Homo sapiens | 1 | assay format | Literature data from EUbOPEN Chemogenomic Library | ||
| 19. | ALA5210259 | B | Affinity On-target Cellular interaction (Cell-based cAMP assay) EUB0000317b GPR52 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library | ||
| 20. | ALA5210264 | B | Affinity On-target Cellular interaction (Cell-based cAMP assay) EUB0000336a GPR52 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library |
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