| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1250098 | B | Inhibition of Myc-Max protein-protein interaction by ELISA analysis | 1 | ALA1240300 | protein complex format | Scientific Literature | ||
| 2. | ALA1250099 | B | Inhibition of Myc-Max protein-protein interaction by EMSA | 1 | ALA1240300 | protein complex format | Scientific Literature | ||
| 3. | ALA3223389 | B | Inhibition of c-Myc/Max (unknown origin) DNA-binding activity preincubated for 1 hr followed by DNA addition measured after 15 mins by electrophoretic mobility shift assay | Homo sapiens | 1 | ALA3217750 | protein complex format | Scientific Literature | |
| 4. | ALA3223393 | B | Inhibition of c-Myc/Max (unknown origin) DNA-binding activity | Homo sapiens | 2 | ALA3217750 | protein complex format | Scientific Literature | |
| 5. | ALA3223398 | B | Inhibition of c-Myc/Max (unknown origin) | Homo sapiens | 1 | ALA3217750 | protein complex format | Scientific Literature | |
| 6. | ALA3428716 | B | Disruption of human recombinant c-Myc-Max(S)/DNA (unknown origin) binding assessed as complex level at 100 uM by electrophoretic mobility shift assay relative to control | Homo sapiens | 40 | ALA3425495 | protein complex format | Scientific Literature | |
| 7. | ALA3428717 | B | Disruption of human recombinant c-Myc-Max/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative to control | Homo sapiens | 6 | ALA3425495 | protein complex format | Scientific Literature | |
| 8. | ALA3428718 | B | Disruption of human recombinant Myc(L)-Max(L)/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative to control | Homo sapiens | 6 | ALA3425495 | protein complex format | Scientific Literature | |
| 9. | ALA3428721 | B | Binding affinity to human recombinant 15N labeled c-Myc-Max(S) heterodimer assessed as chemical shift up to 100 uM by NMR spectroscopy | Homo sapiens | 1 | ALA3425495 | protein complex format | Scientific Literature | |
| 10. | ALA3428722 | B | Inhibition of heterodimerization of human recombinant His-tagged c-Myc-Max(S) compound treated for 20 mins with c-Myc and followed by added Max(S) at 6.3 to 50 uM after 30 mins by SPR analysis in presence of biotinylated E-box-containing oligonucleotides | Homo sapiens | 1 | ALA3425495 | protein complex format | Scientific Literature | |
| 11. | ALA3428723 | B | Inhibition of human recombinant His-tagged c-Myc-Max(S) heterodimer binding to DNA at 6.3 to 50 uM after 30 mins by SPR analysis in presence of biotinylated E-box-containing oligonucleotides | Homo sapiens | 1 | ALA3425495 | protein complex format | Scientific Literature | |
| 12. | ALA3428724 | B | Inhibition of heterodimerization of human recombinant His-tagged c-Myc-Max(S) compound treated for 20 mins with c-Myc and followed by added Max(S) at 3.1 to 50 uM after 30 mins by SPR analysis in presence of biotinylated E-box-containing oligonucleotides | Homo sapiens | 1 | ALA3425495 | protein complex format | Scientific Literature | |
| 13. | ALA3428725 | B | Inhibition of human recombinant His-tagged c-Myc-Max(S) heterodimer binding to DNA at 3.1 to 50 uM after 30 mins by SPR analysis in presence of biotinylated E-box-containing oligonucleotides | Homo sapiens | 1 | ALA3425495 | protein complex format | Scientific Literature | |
| 14. | ALA3428880 | B | Induction of dissociation of c-May-Max in human HL60 cells at 40 to 72 uM after 6 hrs by Co-immunoprecipitation (Co-IP) assay | Homo sapiens | 1 | ALA3425495 | cell-based format | Scientific Literature | |
| 15. | ALA3428881 | B | Induction of dissociation of c-May-Max in human HL60 cells at 10 to 30 uM after 6 hrs by Co-immunoprecipitation (Co-IP) assay | Homo sapiens | 1 | ALA3425495 | cell-based format | Scientific Literature | |
| 16. | ALA3992294 | B | Inhibition of recombinant full-length N-terminal hexahistidine-tagged c-Myc (353 to 437 residues) bHLH-ZIP domain (unknown origin) expressed in Escherichia coli BL21 DE3 (pLysS)/human hexahistidine-tagged Max p21 expressed in Escherichia coli M15 (pRep4) assessed as disruption of E-Box DNA binding preincubated for 30 mins with c-Myc followed by Max p21 and E-box element addition measured after 15 mins by electrophoretic mobility shift assay | Homo sapiens | 6 | ALA3991946 | assay format | Patent Bioactivity Data | |
| 17. | ALA3992295 | B | Inhibition of recombinant full-length N-terminal hexahistidine-tagged c-Myc (353 to 437 residues) bHLH-ZIP domain (unknown origin) expressed in Escherichia coli BL21 DE3 (pLysS)/human hexahistidine-tagged Max p21 expressed in Escherichia coli M15 (pRep4) assessed as disruption of E-Box DNA binding at 25 to 50 nM preincubated for 30 mins with c-Myc followed by Max p21 and E-box element measured after 15 mins by electrophoretic mobility shift assay | Homo sapiens | 2 | ALA3991946 | assay format | Patent Bioactivity Data | |
| 18. | ALA4234734 | B | Binding affinity to His-tagged Myc/Max (unknown origin) expressed in Escherichia coli BL21 at 10 uM by Bio-FET analysis | Homo sapiens | 20 | ALA4229470 | assay format | Scientific Literature | |
| 19. | ALA4234740 | B | Inhibition of biotin-labeled EBOX dsDNA binding to Myc-Max (unknown origin) at 10 uM preincubated for 15 mins followed by test compound-protein mixture addition to biotin-labeled EBOX dsDNA immobilized chip measured over 2.5 mins by SPR analysis | Homo sapiens | 20 | ALA4229470 | protein complex format | Scientific Literature | |
| 20. | ALA4383532 | B | Inhibition of Myc-Max (unknown origin) expressed in human LNCAP cells assessed as reduction in transcriptional activity at 25 uM after 1 day by luciferase reporter gene assay relative to control | Homo sapiens | 12 | ALA4382207 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!