| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3243395 | B | Inhibition of human RRM1/RNR2 activity using CDP as substrate assessed as reduction of dCDP production at 100 uM preincubated for 30 mins followed by substrate addition measured after 1 hr by NMR spectroscopy | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 2. | ALA3243397 | B | Inhibition of human RRM1/RNR2 activity using CDP as substrate assessed as reduction of CDP consumption at 100 uM preincubated for 30 mins followed by substrate addition measured after 1 hr by NMR spectroscopy | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 3. | ALA3390459 | B | Inhibition of ribonucleotide reductase in human HL60 cells assessed as intracellular dNTP pools level at 1.2 mM after 1 hr by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3390460 | B | Inhibition of ribonucleotide reductase in human HL60 cells assessed as intracellular dNTP pools level at 0.3 mM after 1 hr by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3390461 | B | Inhibition of ribonucleotide reductase in human HL60 cells assessed as intracellular dNTP pools level at 50 uM after 1 hr by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3390462 | B | Inhibition of human recombinant ribonucleotide reductase at 1.2 mM | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 7. | ALA3390463 | B | Inhibition of human recombinant ribonucleotide reductase at 0.1 mM | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 8. | ALA3390464 | B | Inhibition of human recombinant ribonucleotide reductase at 1.2 mM in presence of 1 mM ATP | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 9. | ALA3390465 | B | Inhibition of human recombinant ribonucleotide reductase at 1.2 mM in presence of 3 mM ATP | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 10. | ALA3390466 | B | Inhibition of human recombinant ribonucleotide reductase at 1.2 mM in presence of dGTP | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 11. | ALA3390467 | B | Competitive inhibition of human recombinant ribonucleotide reductase in presence of varying levels of ATP by Dixon plot | Homo sapiens | 1 | protein complex format | Scientific Literature |
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