| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA953034 | B | Inhibition of Mycobacterium leprae recombinant DNA gyrase expressed in Escherichia coli assessed as inhibition of pBR322 DNA supercoiling | Mycobacterium leprae | 13 | ALA1145475 | organism-based format | Scientific Literature | |
| 2. | ALA953035 | B | Effect on Mycobacterium leprae recombinant DNA gyrase expressed in Escherichia coli assessed as enhancement of supercoiled pBR322 DNA cleavage | Mycobacterium leprae | 13 | ALA1145475 | organism-based format | Scientific Literature | |
| 3. | ALA953036 | F | Antibacterial activity against Mycobacterium leprae at 5 ug/mL after 11 to 18 days | Mycobacterium leprae | 13 | ALA1145475 | organism-based format | Scientific Literature | |
| 4. | ALA953037 | F | Antibacterial activity in Mycobacterium leprae infected mouse foot-pad model assessed as parasite killing at 25 mg/kg/day after 9 months | Mycobacterium leprae | 1 | ALA1145475 | organism-based format | Scientific Literature | |
| 5. | ALA953038 | F | Antibacterial activity in Mycobacterium leprae infected mouse foot-pad model assessed as parasite killing at 150 mg/kg/day after 9 months | Mycobacterium leprae | 2 | ALA1145475 | organism-based format | Scientific Literature | |
| 6. | ALA953039 | F | Antibacterial activity in Mycobacterium leprae infected mouse foot-pad model assessed as parasite killing at >150 mg/kg/day after 9 months | Mycobacterium leprae | 1 | ALA1145475 | organism-based format | Scientific Literature | |
| 7. | ALA953040 | F | Antibacterial activity in Mycobacterium leprae infected mouse foot-pad model assessed as parasite killing at 15 mg/kg/day after 9 months | Mycobacterium leprae | 1 | ALA1145475 | organism-based format | Scientific Literature | |
| 8. | ALA938431 | F | Antibacterial activity in Mycobacterium leprae infected mouse foot-pad model assessed as parasite killing at >300 mg/kg/day after 9 months | Mycobacterium leprae | 1 | ALA1145475 | organism-based format | Scientific Literature | |
| 9. | ALA938432 | F | Antibacterial activity in Mycobacterium leprae infected mouse foot-pad model assessed as parasite killing at 50 mg/kg/day after 9 months | Mycobacterium leprae | 1 | ALA1145475 | organism-based format | Scientific Literature | |
| 10. | ALA938433 | F | Antibacterial activity in Mycobacterium leprae infected mouse foot-pad model assessed as parasite killing after 9 months | Mycobacterium leprae | 6 | ALA1145475 | organism-based format | Scientific Literature | |
| 11. | ALA1055082 | B | Inhibition of Mycobacterium leprae wild type DNA gyrase A2B2 assessed as DNA supercoiling inhibition | Mycobacterium leprae | 7 | ALA1153562 | organism-based format | Scientific Literature | |
| 12. | ALA1055083 | B | Inhibition of Mycobacterium leprae DNA gyrase subunit A G89C mutant assessed as DNA supercoiling inhibition | Mycobacterium leprae | 7 | ALA1153562 | organism-based format | Scientific Literature | |
| 13. | ALA1055084 | B | Inhibition of Mycobacterium leprae DNA gyrase subunit A A91V mutant assessed as DNA supercoiling inhibition | Mycobacterium leprae | 7 | ALA1153562 | organism-based format | Scientific Literature | |
| 14. | ALA1055085 | B | Inhibition of Mycobacterium leprae wild type DNA gyrase subunit B D205N mutant assessed as DNA supercoiling inhibition | Mycobacterium leprae | 7 | ALA1153562 | organism-based format | Scientific Literature | |
| 15. | ALA1055086 | B | Inhibition of Mycobacterium leprae wild type DNA gyrase A2B2 assessed as formation of DNA cleavable complex | Mycobacterium leprae | 7 | ALA1153562 | organism-based format | Scientific Literature | |
| 16. | ALA1055127 | B | Inhibition of Mycobacterium leprae wild type DNA gyrase subunit A G89A mutant assessed as formation of DNA cleavable complex | Mycobacterium leprae | 7 | ALA1153562 | organism-based format | Scientific Literature | |
| 17. | ALA1055128 | B | Inhibition of Mycobacterium leprae wild type DNA gyrase subunit A A91V mutant assessed as formation of DNA cleavable complex | Mycobacterium leprae | 7 | ALA1153562 | organism-based format | Scientific Literature | |
| 18. | ALA1055129 | B | Inhibition of Mycobacterium leprae wild type DNA gyrase subunit B D205N mutant assessed as formation of DNA cleavable complex | Mycobacterium leprae | 7 | ALA1153562 | organism-based format | Scientific Literature | |
| 19. | ALA1055130 | B | Selectivity index, ratio of IC50 for Mycobacterium leprae DNA gyrase subunit A G89C mutant to IC50 for Mycobacterium leprae wild type DNA gyrase A2B2 | Mycobacterium leprae | 3 | ALA1153562 | organism-based format | Scientific Literature | |
| 20. | ALA1055131 | B | Selectivity index, ratio of IC50 for Mycobacterium leprae DNA gyrase subunit A A91V mutant to IC50 for Mycobacterium leprae wild type DNA gyrase A2B2 | Mycobacterium leprae | 3 | ALA1153562 | organism-based format | Scientific Literature |
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