| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1245991 | F | Antifungal activity against Fonsecaea monophora CBS 269.37 | Fonsecaea monophora | 3 | organism-based format | Scientific Literature | ||
| 2. | ALA1245992 | F | Antifungal activity against Fonsecaea monophora CBS 117236 | Fonsecaea monophora | 3 | organism-based format | Scientific Literature | ||
| 3. | ALA1245993 | F | Antifungal activity against 1 x 10'6 CFU Fonsecaea monophora CBS 269.37 infected in OF1 mouse assessed as increase in mouse survival at 20 mg/kg, po qd administered 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA1245994 | F | Antifungal activity against 1 x 10'6 CFU Fonsecaea monophora CBS 269.37 infected in OF1 mouse assessed as increase in mouse survival at 40 mg/kg, po qd administered 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA1245995 | F | Antifungal activity against 2 x 10'5 CFU Fonsecaea monophora CBS 117236 infected in OF1 mouse assessed as increase in mouse survival at 20 mg/kg, po qd administered 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA1245996 | F | Antifungal activity against 2 x 10'5 CFU Fonsecaea monophora CBS 117236 infected in OF1 mouse assessed as increase in mouse survival at 40 mg/kg, po qd administered 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA1245997 | F | Antifungal activity against 2 x 10'5 CFU Fonsecaea monophora CBS 117236 infected in OF1 mouse assessed as increase in mouse survival at 10 mg/kg, po qd administered 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA1245998 | F | Antifungal activity against 1 x 10'6 CFU Fonsecaea monophora CBS 269.37 infected in po dosed OF1 mouse assessed as reduction in fungal load in spleen compound administered qd 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA1245999 | F | Antifungal activity against 1 x 10'6 CFU Fonsecaea monophora CBS 269.37 infected in po dosed OF1 mouse assessed as reduction in fungal load in kidney compound administered qd 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA1246000 | F | Antifungal activity against 1 x 10'6 CFU Fonsecaea monophora CBS 269.37 infected in po dosed OF1 mouse assessed as reduction in fungal load in brain compound administered qd 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA1246001 | F | Antifungal activity against 1 x 10'6 CFU Fonsecaea monophora CBS 269.37 infected in po dosed OF1 mouse assessed as reduction in fungal load in lung compound administered qd 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA1246002 | F | Antifungal activity against 1 x 10'6 CFU Fonsecaea monophora CBS 269.37 infected in OF1 mouse assessed as increase in mouse survival at 1.5 mg/kg, ip qd administered 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA1246003 | F | Antifungal activity against 1 x 10'6 CFU Fonsecaea monophora CBS 269.37 infected in OF1 mouse assessed as increase in mouse survival at 25 mg/kg, po bid administered 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA1246004 | F | Antifungal activity against 2 x 10'5 CFU Fonsecaea monophora CBS 117236 infected in OF1 mouse assessed as increase in mouse survival at 25 mg/kg, po bid administered 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA1246005 | F | Antifungal activity against 2 x 10'5 CFU Fonsecaea monophora CBS 117236 infected in po dosed OF1 mouse assessed as reduction in fungal load in spleen compound administered qd 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA1246006 | F | Antifungal activity against 2 x 10'5 CFU Fonsecaea monophora CBS 117236 infected in po dosed OF1 mouse assessed as reduction in fungal load in kidney compound administered qd 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA1246007 | F | Antifungal activity against 2 x 10'5 CFU Fonsecaea monophora CBS 117236 infected in po dosed OF1 mouse assessed as reduction in fungal load in brain compound administered qd 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA1246008 | F | Antifungal activity against 2 x 10'5 CFU Fonsecaea monophora CBS 117236 infected in po dosed OF1 mouse assessed as reduction in fungal load in lung compound administered qd 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA1246009 | F | Antifungal activity against 2 x 10'5 CFU Fonsecaea monophora CBS 117236 infected in po dosed OF1 mouse assessed as reduction in fungal load in spleen at 1.5 mg/kg, ip qd administered 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA1246010 | F | Antifungal activity against 2 x 10'5 CFU Fonsecaea monophora CBS 117236 infected in po dosed OF1 mouse assessed as reduction in fungal load in kidney at 1.5 mg/kg, ip qd administered 1 day after infection for 7 days | Fonsecaea monophora | 1 | organism-based format | Scientific Literature |
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