# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA872505 | Binding | Inhibition of protein kinase Jak 3 | Homo sapiens | 1 | ALA1135866 | single protein format | Scientific Literature | |
2. | ALA704113 | Binding | Inhibitory activity against Janus Kinase 3 protein tyrosine kinase. | 18 | ALA1136217 | single protein format | Scientific Literature | ||
3. | ALA704114 | Functional | Inhibition of Janus kinase 3 phosphorylation at 3 uM | Homo sapiens | 3 | ALA1136217 | assay format | Scientific Literature | |
4. | ALA704115 | Binding | Inhibition of Jak3 kinase | 1 | ALA1136358 | single protein format | Scientific Literature | ||
5. | ALA704116 | Binding | Inhibition of Janus kinase 3 | 1 | ALA1136216 | single protein format | Scientific Literature | ||
6. | ALA704117 | Binding | In vitro inhibition of Janus kinase 3. | 18 | ALA1133428 | single protein format | Scientific Literature | ||
7. | ALA704118 | Binding | Inhibition of Janus kinase 3 | 1 | ALA1136271 | single protein format | Scientific Literature | ||
8. | ALA1292867 | Binding | Inhibition of human recombinant JAK3 by TR-FRET assay | Homo sapiens | 18 | ALA1287810 | single protein format | Scientific Literature | |
9. | ALA1292872 | Binding | Binding affinity to JAK3 | 2 | ALA1287810 | single protein format | Scientific Literature | ||
10. | ALA1292171 | Binding | Inhibition of Jak3 | 1 | ALA1287714 | single protein format | Scientific Literature | ||
11. | ALA1051335 | Binding | Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domain | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
12. | ALA1061988 | Binding | Selectivity for JAK3 as proportion of 290 kinases in screen with similar potency; non-selective = 1 highly selective = 0 | Homo sapiens | 1 | ALA1150977 | single protein format | Scientific Literature | |
13. | ALA1047360 | Binding | Inhibition of JAK3 at 100 uM | 1 | ALA1154652 | single protein format | Scientific Literature | ||
14. | ALA1049094 | Binding | Inhibition of JAK3 kinase domain 2 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
15. | ALA1038676 | Binding | Inhibition of JAK3 | 1 | ALA1154622 | single protein format | Scientific Literature | ||
16. | ALA1042392 | Binding | Inhibition of recombinant JAK3 | 1 | ALA1154754 | single protein format | Scientific Literature | ||
17. | ALA1042394 | Binding | Inhibition of JAK3 in human HT2 cells assessed as inhibition of IL2-induced STAT5 phosphorylation by flow cytometry | Homo sapiens | 1 | ALA1154754 | cell-based format | Scientific Literature | |
18. | ALA1038362 | Binding | Inhibition of Jak3 | 1 | ALA1155349 | single protein format | Scientific Literature | ||
19. | ALA1040668 | Binding | Residual activity of JAK3 at 0.1 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature | ||
20. | ALA1041126 | Binding | Residual activity of JAK3 at 1 uM by microplate scintillation counting | 3 | ALA1152560 | single protein format | Scientific Literature |