| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1107474 | F | Antagonist activity at FLAG-tagged human BLT2 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization preincubated for 10 mins before LTB4 challenge | 5 | ALA1158546 | cell-based format | Scientific Literature | ||
| 2. | ALA3417946 | B | Inhibition of BLT2 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA3414472 | single protein format | Scientific Literature | |
| 3. | ALA4627066 | B | Displacement of [3H]LTB4 from HA-epitope tagged human BLT2 expressed in CHOK1 cells incubated for 60 mins by liquid scintillation counting method | Homo sapiens | 3 | ALA4622988 | cell-based format | Scientific Literature | |
| 4. | ALA4627068 | B | Agonist activity at HA-epitope tagged human BLT2 expressed in CHOK1 cells assessed as induction of chemotactic motility at 100 nM incubated for 2 hrs by hematoxylin and eosin staining based optical microscopic method | Homo sapiens | 2 | ALA4622988 | cell-based format | Scientific Literature | |
| 5. | ALA4627069 | B | Agonist activity at HA-epitope tagged human BLT2 expressed in CHOK1 cells assessed as induction of chemotactic motility at 300 nM incubated for 2 hrs by hematoxylin and eosin staining based optical microscopic method | Homo sapiens | 2 | ALA4622988 | cell-based format | Scientific Literature | |
| 6. | ALA4627070 | B | Agonist activity at HA-epitope tagged human BLT2 expressed in CHOK1 cells assessed as induction of chemotactic motility incubated for 2 hrs by hematoxylin and eosin staining based optical microscopic method | Homo sapiens | 1 | ALA4622988 | cell-based format | Scientific Literature | |
| 7. | ALA4627071 | B | Partial agonist activity at HA-epitope tagged human BLT2 expressed in CHOK1 cells assessed as induction of chemotactic motility incubated for 2 hrs by hematoxylin and eosin staining based optical microscopic method | Homo sapiens | 2 | ALA4622988 | cell-based format | Scientific Literature | |
| 8. | ALA4730477 | B | Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation at 20 uM incubated for 90 mins by IP-one assay relative to basal level | Homo sapiens | 1 | ALA4725415 | cell-based format | Scientific Literature | |
| 9. | ALA4730478 | B | Inhibition of human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as IP-1 accumulation at 50 uM incubated for 90 mins by IP-one assay relative to basal level | Homo sapiens | 1 | ALA4725415 | cell-based format | Scientific Literature | |
| 10. | ALA4730490 | B | Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation incubated for 90 mins by IP-one assay | Homo sapiens | 51 | ALA4725415 | cell-based format | Scientific Literature | |
| 11. | ALA4730491 | B | Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation incubated for 90 mins by IP-one assay relative to CAY10583 | Homo sapiens | 40 | ALA4725415 | cell-based format | Scientific Literature | |
| 12. | ALA4730492 | B | Inhibition of human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as IP-1 accumulation at >10 uM incubated for 90 mins by IP-one assay relative to basal level | Homo sapiens | 2 | ALA4725415 | cell-based format | Scientific Literature | |
| 13. | ALA4730495 | B | Inhibition of human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as IP-1 accumulation at >50 uM incubated for 90 mins by IP-one assay relative to basal level | Homo sapiens | 1 | ALA4725415 | cell-based format | Scientific Literature | |
| 14. | ALA4839253 | F | Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assay | Homo sapiens | 22 | ALA4837242 | cell-based format | Scientific Literature | |
| 15. | ALA4839254 | F | Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate by measuring efficacy at 20 uM measured after 90 mins by HTRF assay relative to CAY10583 | Homo sapiens | 11 | ALA4837242 | cell-based format | Scientific Literature | |
| 16. | ALA4883520 | B | PRESTO-Tango GPCRome screening (LTB4R2B) | 1 | ALA4507309 | single protein format | Donated Chemical Probes - SGC Frankfurt |
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