# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA808364 | B | The binding affinity was measured on TRH receptor using [3H]- MeTRH as radioligand. | 2 | ALA1127031 | single protein format | Scientific Literature | ||
2. | ALA828971 | B | Inhibition of [3H][3-Me-His2]-TRH binding to thyrotropin releasing hormone receptor of rat forebrain | Rattus norvegicus | 5 | ALA1137824 | assay format | Scientific Literature | |
3. | ALA872292 | B | Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degree C for 1 hr at pH 7.4 using [3H]Ntau(1)-Me-His-TRH | 6 | ALA1141095 | cell-based format | Scientific Literature | ||
4. | ALA883661 | B | Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degree C for 1 hr at pH 7.4 using [3H]Ntau(1)-Me-His-TRH; Range = 0.27-0.37 uM | 1 | ALA1141095 | cell-based format | Scientific Literature | ||
5. | ALA883664 | B | Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degree C for 1 hr at pH 7.4 using [3H]Ntau(1)-Me-His-TRH; Range = 0.001-0.003 uM | 1 | ALA1141095 | cell-based format | Scientific Literature | ||
6. | ALA884981 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8 | 6 | ALA1141095 | cell-based format | Scientific Literature | ||
7. | ALA872069 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8; Range = 0.16-0.51 uM | 1 | ALA1141095 | cell-based format | Scientific Literature | ||
8. | ALA872189 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8; Range = 0.002-0.004 uM | 1 | ALA1141095 | cell-based format | Scientific Literature | ||
9. | ALA3102193 | B | Inhibition of rat TRH receptor at 10 uM relative to control | Rattus norvegicus | 1 | ALA3098111 | single protein format | Scientific Literature | |
10. | ALA3880464 | B | Displacement of [3H]-3MeHis-TRH from TRH receptor in Sprague-Dawley rat cortical membranes | Rattus norvegicus | 3 | ALA3880382 | assay format | Patent Bioactivity Data | |
11. | ALA4603333 | B | Inhibition of rat TRH receptor at 10 uM relative to control | Rattus norvegicus | 1 | ALA4602617 | single protein format | Scientific Literature |