| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA829360 | B | Inhibitory concentration against MurA enzyme in Escherichia coli | Escherichia coli | 28 | single protein format | Scientific Literature | ||
| 2. | ALA859884 | B | Inhibitory activity against MurA in Escherichia coli | Escherichia coli | 27 | single protein format | Scientific Literature | ||
| 3. | ALA911296 | B | Inhibition of Escherichia coli K12 Mur A in presence of UNAG | Escherichia coli | 9 | single protein format | Scientific Literature | ||
| 4. | ALA911298 | B | Inhibition of Escherichia coli K12 Mur A C115D at 50 uM in presence of UNAG | Escherichia coli | 9 | single protein format | Scientific Literature | ||
| 5. | ALA928525 | B | Inhibition of Escherichia coli MurA C115D mutant | Escherichia coli | 2 | assay format | Scientific Literature | ||
| 6. | ALA1220490 | B | Inhibition of IPTG-stimulated Escherichia coli K-12 murA at 16 fold MIC by microarray analysis | Escherichia coli K-12 | 1 | single protein format | Scientific Literature | ||
| 7. | ALA1220504 | B | Inhibition of IPTG-stimulated Escherichia coli K-12 murA at 8 fold MIC by microarray analysis | Escherichia coli K-12 | 1 | single protein format | Scientific Literature | ||
| 8. | ALA1218513 | B | Inhibition of IPTG-stimulated Escherichia coli K-12 murA at 4 fold MIC by microarray analysis | Escherichia coli K-12 | 2 | single protein format | Scientific Literature | ||
| 9. | ALA2341693 | A | Induction of Escherichia coli MurA-mediated 2-bromo-5-(2-nitrovinyl)furan formation assessed as enzyme-(R)-methyl 3-mercapto-2-(6-methoxy-2-oxo-2H-chromene-3-carboxamido)propanoate adduct level at 200 uM after 1 hr by SDS-PAGE analysis in presence of thiol nucleophile DTT in reducing laemmli buffer | Escherichia coli | 1 | single protein format | Scientific Literature | ||
| 10. | ALA2341694 | A | Induction of Escherichia coli MurA-mediated 2-bromo-5-(2-nitrovinyl)furan formation assessed as enzyme-(R)-methyl 3-mercapto-2-(6-methoxy-2-oxo-2H-chromene-3-carboxamido)propanoate adduct level at 200 to 300 uM after 1 hr by SDS-PAGE analysis | Escherichia coli | 1 | single protein format | Scientific Literature | ||
| 11. | ALA2341695 | A | Prodrug conversion assessed as Escherichia coli MurA-mediated 2-bromo-5-(2-nitrovinyl)furan formation at 100 uM by HPLC-UV analysis | Escherichia coli | 1 | single protein format | Scientific Literature | ||
| 12. | ALA2341697 | B | Inhibition of Escherichia coli MurA C115D mutant expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate at 50 to 500 uM incubated for 30 mins by 2,2'-dithiopyridine based spectrophotometric analysis | Escherichia coli | 2 | assay format | Scientific Literature | ||
| 13. | ALA2341698 | B | Inhibition of Escherichia coli MurA expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate at 50 to 500 uM incubated for 30 mins by 2,2'-dithiopyridine based spectrophotometric analysis | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 14. | ALA2341707 | B | Irreversible inhibition of Escherichia coli MurA expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate at 100 nM incubated up to 80 min prior to PEP addition measured after 60 mins by spectrophotometric analysis | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 15. | ALA2341710 | B | Irreversible inhibition of Escherichia coli MurA expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate at 1.25 uM incubated up to 80 min prior to PEP addition measured after 60 mins by spectrophotometric analysis | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 16. | ALA2341711 | B | Inhibition of Escherichia coli MurA expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate at 200 nM incubated for 10 mins prior to UNAG and PEP addition measured after 60 mins by spectrophotometric analysis | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 17. | ALA2341712 | B | Inhibition of Escherichia coli MurA expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate at 5 uM incubated for 10 mins prior to UNAG and PEP addition measured after 60 mins by spectrophotometric analysis | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 18. | ALA2339336 | B | Inhibition of Escherichia coli MurA C115D mutant expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate incubated for 10 mins prior to PEP addition measured after 60 mins by spectrophotometric analysis | Escherichia coli | 7 | assay format | Scientific Literature | ||
| 19. | ALA2339337 | B | Inhibition of Escherichia coli MurA expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate incubated for 10 mins prior to PEP addition measured after 60 mins by spectrophotometric analysis | Escherichia coli | 7 | assay format | Scientific Literature | ||
| 20. | ALA4003955 | B | Inhibition of Escherichia coli K-12 MBP-fused C-terminal His-tagged MurA (6508 to 7768 residues) using UNAG as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins in presence of PEP by malachite green dye based spectrophotometric method | Escherichia coli K-12 | 1 | single protein format | Scientific Literature |
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