| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA807607 | F | Rate of phosphorylation of labeled sphingosine derivative by by human SPHK-2 expressed in HEK293 cells relative to rate of D-sphingosine | 8 | cell-based format | Scientific Literature | |||
| 2. | ALA864560 | B | Rate of phosphorylation by recombinant human SPHK2 using | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 3. | ALA902399 | B | Effect on rate of phosphorylation of human recombinant SPHK2 expressed in HEK293 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA995443 | B | Inhibition of human cloned SPHK2 expressed in CHO cells at 10 uM | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 5. | ALA995445 | B | Inhibition of human cloned SPHK2 expressed in CHO cells using D-erythro-sphingosine as substrate by Michaelis-Menten plot | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA995448 | B | Effect on human cloned SPHK2 activity expressed in CHO cells at 10 uM relative to basal level | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 7. | ALA995452 | B | Inhibition of human SPHK2 expressed in human U937 cells assessed as inhibition of endogenous sphingosine-1-phosphate levels at 5 uM after 2 hrs by ELISA | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA1032134 | B | Inhibition of SphK2 | 8 | single protein format | Scientific Literature | |||
| 9. | ALA1051863 | B | Activity at human SPHK2 at 15 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA1051864 | B | Activity at human SPHK2 at 100 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA1052797 | B | Inhibition of sphingosine kinase 2 at 10 uM | 27 | single protein format | Scientific Literature | |||
| 12. | ALA1110618 | B | Induction of human SphK2 phosphorylation | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 13. | ALA1291275 | B | Inhibition of sphingosine kinase 2 | 1 | single protein format | Scientific Literature | |||
| 14. | ALA1291276 | B | Inhibition of sphingosine kinase 2 up to 25 uM | 1 | single protein format | Scientific Literature | |||
| 15. | ALA1777262 | B | Inhibition of SPHK2 | 1 | single protein format | Scientific Literature | |||
| 16. | ALA1821103 | B | Inhibition of N-terminal GST-fused sphingosine kinase 2 (1-618) expressed in baculovirus expression system assessed as inhibition of sphingosine phosphorylation after 1 hr by off-chip mobility shift assay | 9 | assay format | Scientific Literature | |||
| 17. | ALA1929797 | B | Inhibition of SphK2 in human U937 cells assessed as change in S1P level by LC/MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA1929798 | B | Inhibition of SphK2 in human U937 cells using FTY720 as substrate assessed as decrease in phosphorylated FTY720 at 10 uM after 2 hrs by LC/MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA1929799 | B | Inhibition of SphK2 in human U937 cells using FTY720 as substrate assessed as accumulation of FTY720 at 10 uM after 2 hrs by LC/MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA1929800 | B | Inhibition of SphK2 in human U937 cells assessed as decrease in Akt phosphorylation after 16 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |
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