| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1220164 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 30 uM by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 2 | assay format | Scientific Literature | ||
| 2. | ALA1220165 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 50 uM by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 9 | assay format | Scientific Literature | ||
| 3. | ALA1220166 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 10 uM by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 4. | ALA1220167 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 5 uM by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 5. | ALA1220168 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 6. | ALA1220169 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 30 uM in presence of 5 mg/ml BSA by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 2 | assay format | Scientific Literature | ||
| 7. | ALA1220170 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 50 uM in presence of 5 mg/ml BSA by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 9 | assay format | Scientific Literature | ||
| 8. | ALA1220171 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 10 uM in presence of 5 mg/ml BSA by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 9. | ALA1220172 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 5 uM in presence of 5 mg/ml BSA by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 10. | ALA1220294 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 50 uM in presence of 0.5% seed fibres by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 11. | ALA1220295 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 50 uM in presence of 1% seed fibres by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 12. | ALA1220296 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 50 uM in presence of 5% seed fibres by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 13. | ALA1220297 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as coating of prion protein with colonial particles at 100 uM by transmission electron microscopy | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 14. | ALA1220299 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of fiber formation at 100 uM by transmission electron microscopy | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 15. | ALA1220301 | B | Inhibition of yeast prion protein Sup35 infection of PSI yeast spheroplast cells at 200 uM | Saccharomyces cerevisiae | 6 | assay format | Scientific Literature | ||
| 16. | ALA1220302 | B | Inhibition of yeast prion protein Sup35 infection of PSI yeast spheroplast cells at 100 uM | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 17. | ALA1220303 | B | Inhibition of yeast prion protein Sup35 infection of PSI yeast spheroplast cells | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
| 18. | ALA1220853 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 100 uM by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 2 | assay format | Scientific Literature | ||
| 19. | ALA1220854 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization preincubation of seed fibers and compound for 5 mins at 100 uM by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 2 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!