| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1220153 | B | Inhibition of human Mre11 nuclease activity at 100 uM | Homo sapiens | 1 | ALA1212698 | single protein format | Scientific Literature | |
| 2. | ALA1220155 | B | Inhibition of human Mre11 ExoIII nuclease activity at 100 uM | Homo sapiens | 1 | ALA1212698 | single protein format | Scientific Literature | |
| 3. | ALA3377972 | B | Inhibition of Mre11 exonuclease activity (unknown origin) in cell free extracts | Homo sapiens | 1 | ALA3352588 | single protein format | Scientific Literature | |
| 4. | ALA3377973 | B | In vitro inhibition of purified recombinant Mre11 exonuclease activity (unknown origin) | Homo sapiens | 1 | ALA3352588 | single protein format | Scientific Literature | |
| 5. | ALA3377974 | B | Inhibition of Mre11 in HEK293 cells assessed as reduction in DSP-induced homologous recombination expressing DR-GFP construct at 25 uM | Homo sapiens | 1 | ALA3352588 | cell-based format | Scientific Literature | |
| 6. | ALA4418119 | B | Inhibition of MRE11 in HU-treated BRCA2/BODIL depleted in human U2OS cells assessed as induction of nascent DNA degradation by measuring reduction in P-RPA foci at 50 uM | Homo sapiens | 2 | ALA4417634 | cell-based format | Patent Bioactivity Data | |
| 7. | ALA4418120 | B | Inhibition of MRE11 in HU-treated BRCA2/BODIL depleted in human U2OS cells assessed as induction of nascent DNA degradation by measuring reduction in P-RPA foci | Homo sapiens | 1 | ALA4417634 | cell-based format | Patent Bioactivity Data |
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