# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3602079 | Binding | Inhibition of JAK1 in mouse BMDM assessed as inhibition of IFNbeta-induced STAT1 phosphorylation at 5 uM preincubated for 3 hrs followed by IFNbeta induction measured after 30 mins by immunoblotting | Mus musculus | 3 | ALA3600288 | single protein format | Scientific Literature | |
2. | ALA3817420 | Binding | Inhibition of FLAG-tagged mouse JAK1 expressed in insect Sf9 cells using biotin-EQEDEPEGDYFEWLE-NH2 as substrate by HTRF assay | Mus musculus | 1 | ALA3813615 | cell-based format | Scientific Literature | |
3. | ALA704108 | Binding | Inhibition of murine Jak 1 protein kinase | Mus musculus | 1 | ALA1135866 | single protein format | Scientific Literature | |
4. | ALA937051 | Binding | Inhibition of mouse JAK1 | Mus musculus | 1 | ALA1145498 | single protein format | Scientific Literature | |
5. | ALA3118989 | Binding | Inhibition of JAK-1 in mouse CTLL cells assessed as inhibition of IL-2-induced stat5 phosphorylation | Mus musculus | 1 | ALA3112442 | cell-based format | Scientific Literature | |
6. | ALA3117012 | Binding | Inhibition of Jak1 in mouse BA/F3 cells expressing TEL-Jak1 assessed as inhibition of STAT5 phosphorylation by Western blotting analysis | Mus musculus | 1 | ALA3112447 | cell-based format | Scientific Literature | |
7. | ALA4181461 | Binding | Inhibition of JAK1 in LPS-stimulated mouse RAW264.7 cells assessed as reduction in STAT3 phosphorylation at Y707 residue pretreated for 1 hr followed by LPS-stimulation by Western blot analysis | Mus musculus | 1 | ALA4177665 | cell-based format | Scientific Literature | |
8. | ALA4181484 | Binding | Inhibition of JAK1 in LPS-stimulated mouse RAW264.7 cells assessed as reduction in STAT1 phosphorylation at S727 residue pretreated for 1 hr followed by LPS-stimulation by Western blot analysis | Mus musculus | 1 | ALA4177665 | cell-based format | Scientific Literature | |
9. | ALA4181485 | Binding | Inhibition of JAK1 in LPS-stimulated mouse RAW264.7 cells assessed as reduction in STAT1 phosphorylation at Y701 residue pretreated for 1 hr followed by LPS-stimulation by Western blot analysis | Mus musculus | 1 | ALA4177665 | cell-based format | Scientific Literature | |
10. | ALA4482166 | Binding | Inhibition of zymosan-induced JAK1 phosphorylation in mouse MHS cells preincubated for 30 mins followed by zymosan challenge and measured after 6 to 24 hrs by Western blot analysis | Mus musculus | 1 | ALA4480455 | cell-based format | Scientific Literature | |
11. | ALA4482168 | Binding | Inhibition of zymosan-induced JAK1 phosphorylation in mouse MHS cells assessed as phosphorylated JAK1 level at 1.5 ug/ml by Western blot analysis relative to tubulin (Rvb = 2.2 No_unit) | Mus musculus | 1 | ALA4480455 | cell-based format | Scientific Literature | |
12. | ALA4482169 | Binding | Inhibition of zymosan-induced JAK1 phosphorylation in mouse MHS cells assessed as phosphorylated JAK1 level at 15 ug/ml by Western blot analysis relative to tubulin (Rvb = 2.2 No_unit) | Mus musculus | 1 | ALA4480455 | cell-based format | Scientific Literature | |
13. | ALA4482172 | Binding | Effect on JAK1 phosphorylation in mouse MHS cells assessed as phosphorylated JAK1 level at 15 ug/ml by Western blot analysis relative to tubulin (Rvb = 1 No_unit) | Mus musculus | 1 | ALA4480455 | cell-based format | Scientific Literature | |
14. | ALA5245500 | Binding | Inhibition of N-terminal flag tagged mouse JAK1 expressed in baculovirus infected Sf9 cells using biotin-EQEDEPEGDYFEWLE-NH2 as substrate in the presence of [gamma p33]-ATP by FRET assay | Mus musculus | 1 | ALA5244234 | cell-based format | Scientific Literature |