#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3428236	Binding	Inhibition of RSK1 (unknown origin) assessed as remaining activity at 100 uM by radioactive filter binding assay in presence of [33P]-ATP relative to control	Homo sapiens	16	ALA3425453	single protein format	Scientific Literature
2.	ALA3607886	Binding	Binding affinity to DNA-tagged RSK1 N-terminal kinase domain (unknown origin) assessed as level of protein captured on solid support at 10 uM by qPCR analysis relative to control	Homo sapiens	1	ALA3603810	single protein format	Scientific Literature
3.	ALA3606883	Binding	Inhibition of RSK1 (unknown origin) at 2 uM by radioactive filter-binding assay	Homo sapiens	1	ALA3603808	single protein format	Scientific Literature
4.	ALA3606974	Binding	Inhibition of RSK1 (unknown origin) at 250 nM by radioactive filter-binding assay	Homo sapiens	1	ALA3603808	single protein format	Scientific Literature
5.	ALA3624366	Binding	Inhibition of human recombinant Rsk1	Homo sapiens	1	ALA3621115	single protein format	Scientific Literature
6.	ALA3631327	Binding	Inhibition of RSK1 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay	Homo sapiens	3	ALA3627608	single protein format	Scientific Literature
7.	ALA3707977	Binding	Kinase Inhibition Assay: The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase inhibition assay for the kinases. Compounds were tested in 5 dose IC50 mode with 10-fold serial dilution starting at 10 μM. Staurosporine, a known protein kinase inhibitor, was tested in 5-dose IC50 mode with 3-fold serial dilution starting at 20 μM. Reactions were carried out in 10 μM ATP. The results are shown in Table 5. The results show that the compound of Example 39 is a kinase inhibitor highly selective for the kinase Plk2.	Homo sapiens	2	ALA3639034	single protein format	BindingDB Database
8.	ALA3734504	Binding	Inhibition of recombinant human RSK1 using fluorescein-labeled peptide as substrate by fluorescence-electrophoretic mobility shift assay	Homo sapiens	1	ALA3727354	single protein format	Patent Bioactivity Data
9.	ALA3737501	Binding	Inhibition of RSK1 (unknown origin) at 1 uM by selectscreen kinase profiling assay in presence of ATP	Homo sapiens	1	ALA3734692	single protein format	Scientific Literature
10.	ALA3743113	Binding	Inhibition of RSK1 (unknown origin) at 30 uM by microfluidic assay relative to control	Homo sapiens	19	ALA3739348	single protein format	Scientific Literature
11.	ALA3750034	Binding	Inhibition of human RSK1 using [KKLNRTLSVA] as substrate	Homo sapiens	1	ALA3745707	single protein format	Scientific Literature
12.	ALA3751108	Binding	Inhibition of Rsk1 (unknown origin) at 1 uM	Homo sapiens	1	ALA3745631	single protein format	Scientific Literature
13.	ALA3756065	Binding	Inhibition of recombinant human RSK1 by radiometric assay in presence of [gamma-33P]-ATP	Homo sapiens	1	ALA3751668	single protein format	Scientific Literature
14.	ALA3757132	Binding	Inhibition of recombinant human RSK1 assessed as residual activity at 1 uM by radiometric assay in presence of [gamma-33P]-ATP relative to control	Homo sapiens	1	ALA3751668	single protein format	Scientific Literature
15.	ALA3761180	Binding	Inhibition of RSK1 (unknown origin) at 100 nM	Homo sapiens	2	ALA3758169	single protein format	Scientific Literature
16.	ALA3777757	Binding	Inhibition of N-terminal His6-tagged recombinant human RSK1 expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control	Homo sapiens	3	ALA3774357	cell-based format	Scientific Literature
17.	ALA3777419	Binding	Inhibition of recombinant RSK1 (unknown origin) assessed as residual activity at 1 uM relative to control	Homo sapiens	1	ALA3774312	single protein format	Scientific Literature
18.	ALA3776415	Binding	Inhibition of human RSK1 (1 to 735 residues) at 1 uM by radioactive [33P]-ATP filter binding assay	Homo sapiens	1	ALA3774338	single protein format	Scientific Literature
19.	ALA3789282	Binding	Inhibition of human RSK1 at 1 uM after 30 mins by fluorescence assay in presence of ATP	Homo sapiens	1	ALA3784918	single protein format	Scientific Literature
20.	ALA3804621	Binding	Inhibition of partial length wild type human RSK1(Kin.Dom.1-N-terminal) expressed in bacterial system assessed as enzyme activity at 1 uM relative to control	Homo sapiens	1	ALA3797029	assay format	Scientific Literature