# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA846736 | Binding | In vitro for its binding affinity to rat V2 receptor | Rattus norvegicus | 5 | ALA1133322 | single protein format | Scientific Literature | |
2. | ALA857675 | Binding | Inhibition of [3H]-AVP binding to isolated rat kidney medullary V2 receptor | Rattus norvegicus | 2 | ALA1143639 | single protein format | Scientific Literature | |
3. | ALA907380 | Binding | Displacement of [3H]AVP from vasopressin V2 receptor in rat kidney membranes | Rattus norvegicus | 23 | ALA1141418 | cell membrane format | Scientific Literature | |
4. | ALA907386 | Functional | Activity at vasopressin V2 receptor in rat kidney membranes assessed as adenylate cyclase activity | Rattus norvegicus | 7 | ALA1141418 | cell membrane format | Scientific Literature | |
5. | ALA907387 | Functional | Activity at vasopressin V2 receptor in rat kidney membranes assessed as maximal adenylate cyclase activity relative to AVP | Rattus norvegicus | 6 | ALA1141418 | cell membrane format | Scientific Literature | |
6. | ALA942881 | Functional | Antagonist activity at rat vasopressin V2 receptor expressed in HEK293 cells assessed as inhibition of Arg-vasopressin-induced cAMP levels | Rattus norvegicus | 1 | ALA1140572 | cell-based format | Scientific Literature | |
7. | ALA1253105 | Binding | Displacement of [3H]vasopressin from vasopressin V2 receptor in rat kidney tissue | Rattus norvegicus | 6 | ALA1250454 | assay format | Scientific Literature | |
8. | ALA1253122 | Binding | Displacement of [3H]vasopressin from rat vasopressin V2 receptor expressed in CHO cells | Rattus norvegicus | 1 | ALA1250454 | cell-based format | Scientific Literature | |
9. | ALA784739 | Functional | Dose that reduces urine flow in water-loaded rats | 16 | ALA1125295 | tissue-based format | Scientific Literature | ||
10. | ALA817090 | Binding | Dose required to lower urine osmolality to 300 mOsm/kg in rat | 8 | ALA1124391 | tissue-based format | Scientific Literature | ||
11. | ALA817091 | Binding | Dose required to lower urine osmolality to 300 mOsm/kg in rat; NT=Not tested | 1 | ALA1124391 | tissue-based format | Scientific Literature | ||
12. | ALA817092 | Binding | Ability to displace [3H]- Arginine Vasopressin (AVP) from its specific binding sites in rat liver (V2 receptor) | 57 | ALA1126733 | assay format | Scientific Literature | ||
13. | ALA878965 | Binding | Ability to inhibit AVP stimulation of adenylate cyclase activity in the rat kidney medulla (AVP-V2) receptor | 2 | ALA1125324 | single protein format | Scientific Literature | ||
14. | ALA817094 | Binding | Inhibition of [3H]arginine vasopressin binding to AVP-V2 site in rat kidney medulla. | 21 | ALA1125324 | tissue-based format | Scientific Literature | ||
15. | ALA817095 | Binding | Concentration required to displace 50% of [3H]arginine vasopressin from rat kidney medullary (AVP-V2a site) | 2 | ALA1125324 | single protein format | Scientific Literature | ||
16. | ALA817096 | Binding | In vitro inhibition of (P[3H]-AVP binding to isolated rat kidney medullary V2 receptor | 1 | ALA1131758 | single protein format | Scientific Literature | ||
17. | ALA817097 | Binding | Displacement of P[3H]-AVP from isolated rat kidney medullary V2 receptor | Rattus norvegicus | 15 | ALA1131758 | single protein format | Scientific Literature | |
18. | ALA817098 | Binding | In vitro inhibition of [3H]AVP binding to rat V2 receptor | 1 | ALA1131757 | single protein format | Scientific Literature | ||
19. | ALA817099 | Binding | Inhibition of radioligand [3H]-AVP binding to the vasopressin V2 receptor in rat kidney tissue | 159 | ALA1126550 | assay format | Scientific Literature | ||
20. | ALA817100 | Binding | In vitro inhibition of (P[3H]-AVP binding towards isolated rat kidney medullary V2 receptor at a dose of 10 uM | 2 | ALA1131758 | single protein format | Scientific Literature |
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