# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3361956 | B | Agonist activity at human TAS2R4 expressed in U2OS cells by Ga16gust44 Clone 2B FLIPR/summary (Abse5) assay | Homo sapiens | 1 | ALA3351646 | cell-based format | Scientific Literature | |
2. | ALA4346424 | F | Antagonist activity at recombinant human TAS2R4 transiently expressed in HEK293T co-expressing Galpha16gust44 assessed as inhibition of chloroquine-induced intracellular calcium level by measuring remaining activity at 25 uM by fluo-4AM dye based FLIPR assay relative to control | Homo sapiens | 2 | ALA4342523 | cell-based format | Scientific Literature | |
3. | ALA4419002 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R4 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4418912 | cell-based format | Patent Bioactivity Data | |
4. | ALA4419036 | F | Antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R4 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of colchicine-induced increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 2 | ALA4418912 | cell-based format | Patent Bioactivity Data | |
5. | ALA4419227 | F | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay | Homo sapiens | 2 | ALA4419163 | cell-based format | Patent Bioactivity Data | |
6. | ALA4419252 | F | Agonist activity at human TAS2R4 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level at 20 mM by Calcium-3 dye based fluorescence assay relative to control | Homo sapiens | 3 | ALA4419163 | cell-based format | Patent Bioactivity Data | |
7. | ALA4421739 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R4 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4421717 | cell-based format | Patent Bioactivity Data | |
8. | ALA4421767 | F | Activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R4 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on colchicine-induced intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 2 | ALA4421717 | cell-based format | Patent Bioactivity Data |