# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3369823 | B | Binding affinity to influenza A virus (A/Puerto Rico/8/1934(H1N1)) PB2 by competition binding fluorescence polarization (FP) assay | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 30 | ALA3352362 | single protein format | Scientific Literature | |
2. | ALA4329323 | B | Inhibition of PB2 in Influenza A virus (A/Weiss/1943(H1N1)) infected in MDCK cells assessed as reduction in virus induced cell death after 5 days by CCK-8 assay | Influenza A virus (A/Weiss/1943(H1N1)) | 33 | ALA4325902 | cell-based format | Scientific Literature | |
3. | ALA4385009 | B | Inhibition of fluorescently-labeled m7GTP binding to Influenza A virus RNA polymerase PB2 preincubated for 15 mins followed by m7GTP addition measured after 1 hr by HTRF assay | Influenza A virus | 1 | ALA4382263 | single protein format | Scientific Literature | |
4. | ALA4385010 | B | Binding affinity to Influenza A virus RNA polymerase PB2 by SPR assay | Influenza A virus | 2 | ALA4382263 | single protein format | Scientific Literature | |
5. | ALA5055352 | B | Binding affinity to CM5 immobilized N-terminal His/Sumo tagged Influenza A virus (A/WSN/1933(H1N1)) PB2 CBD (318 to 486 residues) expressed in Escherichia coli by surface plasmon resonance assay | Influenza A virus (A/WSN/1933(H1N1)) | 7 | ALA5053554 | assay format | Scientific Literature | |
6. | ALA5261287 | B | Binding affinity to full length Influenza A virus PB2 cap-binding domain assessed as dissociation constant incubated for 60 mins by fluorescence polarization assay | influenza A virus | 13 | ALA5260803 | single protein format | Scientific Literature |