# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4336776 | B | Induction of YAP nuclear translocation in human A549 cells at 10 uM incubated for 8 hrs by immunofluorescence based confocal microscopy | Homo sapiens | 2 | ALA4334471 | cell-based format | Scientific Literature | |
2. | ALA4419934 | B | Inhibition of YAP1 (unknown origin) assessed as disruption in YAP1/OCT4 interaction by ELISA | Homo sapiens | 33 | ALA4419178 | single protein format | Patent Bioactivity Data | |
3. | ALA4419935 | B | Inhibition of YAP1 (unknown origin) assessed as disruption in YAP1/OCT4 interaction at 5 uM by ELISA relative to control | Homo sapiens | 11 | ALA4419178 | single protein format | Patent Bioactivity Data | |
4. | ALA4419936 | B | Inhibition of YAP1 (unknown origin) assessed as disruption in YAP1/OCT4 interaction at 10 uM by ELISA relative to control | Homo sapiens | 7 | ALA4419178 | single protein format | Patent Bioactivity Data | |
5. | ALA4419937 | B | Inhibition of YAP1 (unknown origin) assessed as disruption in YAP1/OCT4 interaction at 50 uM by cell based assay | Homo sapiens | 16 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
6. | ALA4419939 | B | Inhibition of YAP1 in human A549 cells assessed as disruption in YAP1/OCT4 co-localization at 25 uM incubated for 48 hrs by double immunofluorescence based assay | Homo sapiens | 4 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
7. | ALA4419940 | B | Inhibition of YAP1 in human NCI-H1650 cells assessed as disruption in YAP1/OCT4 interaction at 20 to 50 uM incubated for 48 hrs by proximity ligation assay | Homo sapiens | 4 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
8. | ALA4419942 | B | Inhibition of YAP1 in human NCI-H1650 cells assessed as disruption in YAP1/OCT4 interaction at 5 uM incubated for 72 hrs by immunoprecipitation-Westem blot assay | Homo sapiens | 3 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
9. | ALA4419943 | B | Inhibition of YAP1 in human A549 cells assessed as disruption in YAP1/OCT4 interaction at 5 uM incubated for 72 hrs by immunoprecipitation-Westem blot assay | Homo sapiens | 3 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
10. | ALA4419944 | B | Inhibition of YAP1 in human NCI-H1650 cells assessed as reduction in Sox2 protein expression at 5 uM by Western blot analysis | Homo sapiens | 1 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
11. | ALA4419945 | B | Inhibition of YAP1 in human A549 cells assessed as reduction in Sox2 protein expression at 5 uM by Western blot analysis | Homo sapiens | 1 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
12. | ALA4419946 | B | Inhibition of YAP1 in human NCI-H1650 cells assessed as reduction in Sox2 protein expression at 10 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 3 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
13. | ALA4419947 | B | Inhibition of YAP1 in human NCI-H1650 cells assessed as reduction in c-Myc protein expression at 10 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 3 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
14. | ALA4419948 | B | Inhibition of YAP1 in human NCI-H1650 cells assessed as reduction in PDK2 protein expression at 10 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 3 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
15. | ALA4419949 | B | Inhibition of YAP1 in human A549 cells assessed as reduction in Sox2 protein expression at 10 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 3 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
16. | ALA4419950 | B | Inhibition of YAP1 in human A549 cells assessed as reduction in c-Myc protein expression at 10 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 3 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
17. | ALA4419951 | B | Inhibition of YAP1 in human A549 cells assessed as reduction in PDK2 protein expression at 10 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 3 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
18. | ALA4419961 | B | Inhibition of YAP1 in human NCI-H1650 cells assessed as reduction in Sox2 protein expression at 50 uM by luciferase reporter gene assay | Homo sapiens | 1 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
19. | ALA4419963 | B | Inhibition of YAP1 in human NCI-H1650 cells assessed as reduction in Sox2 protein expression at 5 uM by luciferase reporter gene assay | Homo sapiens | 2 | ALA4419178 | cell-based format | Patent Bioactivity Data | |
20. | ALA4419978 | B | Inhibition of YAP1 in human NCI-H1650 cells assessed as suppression of Sox2 mRNA expression at 5 to 10 uM incubated for 72 hrs by RT-PCR method | Homo sapiens | 5 | ALA4419178 | cell-based format | Patent Bioactivity Data |