| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4120894 | B | Binding affinity to human GST-tagged TEAD1 (194 to 411) expressed in Escherichia coli BL21(DE3) by SPR assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA4120895 | B | Inhibition of human His-tagged YAP (50 to 171 residues) interaction with human GST-tagged TEAD1 (194 to 411) expressed in Escherichia coli BL21(DE3) incubated for 30 mins measured by SPR assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 3. | ALA4120897 | B | Inhibition of Gal4-fused TEAD 1 (unknown origin) interaction with YAP expressed in human 293T cells by Dual-Glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4423883 | B | Inhibition of human HEK293 cell lysate derived YAP interaction with recombinant GST-tagged human TEAD1 (194 to 411 residues) expressed in Escherichia coli soluBL21 at 200 uM after 18 hrs by Western blot analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 5. | ALA4423884 | B | Inhibition of GFP-tagged YAP1 (unknown origin) interaction with myc-tagged human TEAD1 expressed in human HeLa cells by measuring GFP-Trap at 200 uM incubated for 30 mins with myc-tagged human TEAD1 lysate followed by GFP-tagged YAP1 lysate addition measured after 30 mins by Western blot based immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4423885 | B | Inhibition of GFP-tagged YAP1 (unknown origin) interaction with myc-tagged human TEAD1 expressed in human HeLa cells by measuring myc-TRAP at 200 uM incubated for 30 mins with myc-tagged human TEAD1 lysate followed by GFP-tagged YAP1 lysate addition measured after 30 mins by Western blot based immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4423886 | B | Inhibition of NL-tagged YAP (unknown origin) interaction with myc-tagged human TEAD1 preincubated for 1 hr followed by NL-tagged YAP addition by NanoGlo assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4423904 | B | Binding affinity to TEAD1 (194 to 411 residues) (unknown origin) by ITC assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4423905 | B | Binding affinity to TEAD1 (194 to 411 residues) (unknown origin) by NMR analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4423906 | B | Inhibition of Gal4-fused TEAD1 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level up to 100 uM after 6 hrs by nanoluciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4423910 | B | Inhibition of Gal4-fused TEAD1 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level after 6 hrs by nanoluciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4670825 | B | Inhibition of CPM binding to nonacylated N-terminal His6/GST-tagged human TEAD1 (209 to 426 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL cells preincubated for 10 mins followed by CPM addition and measured after 1 hr by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5105006 | B | Binding affinity to recombinant TEAD1 (unknown origin) assessed as increase in thermal stability by thermal shift assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA5149028 | B | Binding affinity to human TEAD1 (209 to 426 residues) expressed in Escherichia coli BL21 Star (DE3) by surface plasmon resonance assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA5149039 | B | Binding affinity to human TEAD1 (209 to 426 residues) expressed in Escherichia coli BL21 Star (DE3) assessed as change in melting temperature incubated for 2 hrs by measuring tryptophane fluorescence by Nano Differential scanning fluorometry | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 16. | ALA5149043 | B | Inhibition of pSF-CMV-P-FLAG tagged human TEAD1 palmitoylation transfected in HEK293 cells at 10 uM incubated for 6 hrs by Western blot analysis relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 17. | ALA5149047 | B | Inhibition of pSF-CMV-P-FLAG tagged human TEAD1 palmitoylation transfected in HEK293 cells at 100 nM incubated for 6 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5149050 | B | Binding affinity to human TEAD1 (209 to 426 residues) expressed in Escherichia coli BL21 Star (DE3) assessed as retention time by surface plasmon resonance assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA5149116 | B | Binding affinity to human TEAD1 (209 to 426 residues) expressed in Escherichia coli BL21 Star (DE3) assessed as change in melting temperature incubated for 2 hrs by measuring scattering fluorescence by Nano Differential scanning fluorometry | Homo sapiens | 1 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!