| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3386524 | B | Inhibition of PGM1 (unknown origin) by enzymatic assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA4222106 | B | Inhibition of PGAM1 in human MDA-MB-231 cells using 3-PGA as substrate after 2 hrs in by UV-vis spectrophotometric method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4222107 | B | Inhibition of PGAM1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4222108 | B | Inhibition of recombinant PGAM1 (unknown origin) using 3-PG as substrate preincubated for 2 mins followed by substrate addition | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 5. | ALA4222109 | B | Inhibition of recombinant PGAM1 (unknown origin) at 20 uM using 3-PG as substrate preincubated for 2 mins followed by substrate addition relative to control | Homo sapiens | 19 | single protein format | Scientific Literature | ||
| 6. | ALA4222116 | B | Binding affinity to PGAM1 (unknown origin) assessed as change in melting temperature by SYPRO Orange-dye based fluorescence thermal shift assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4222125 | B | Inhibition of recombinant human PGAM1 using 3-PG as substrate by fluorescence based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4222127 | B | Inhibition of recombinant human His-tagged PGAM1 expressed in Escherichia coli BL21 competent cells by kinase-glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4420385 | B | Binding affinity to human recombinant PGAM1 by tryptophan fluorescence detection based 3-PG competitive binding assay | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
| 10. | ALA4420387 | B | Allosteric binding affinity to human recombinant PGAM1 assessed as increase in fluorescence intensity from compound-unbound form of PGAM1 using increasing concentrations of 3-PG by tryptophan fluorescence detection based 3-PG competitive binding assay | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
| 11. | ALA4420389 | B | Binding affinity to human recombinant PGAM1 by SYPRO orange dye fluorescence based thermal shift assay | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
| 12. | ALA4420390 | B | Inhibition of PGAM1 in human NCI-H1299 cells assessed as reduction in 2-PG levels at 20 uM by spectrophotometry | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 13. | ALA4420391 | B | Inhibition of PGAM1 in human NCI-H1299 cells assessed as increase in 3-PG levels at 20 uM by spectrophotometry | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 14. | ALA4420392 | B | Inhibition of PGAM1 in human NCI-H1299 cells assessed as reduction in 2-PG levels at 20 uM in presence of 5 uM methyl-2-PG by spectrophotometry | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 15. | ALA4420393 | B | Inhibition of PGAM1 in human NCI-H1299 cells assessed as increase in 3-PG levels at 20 uM in presence of 5 uM methyl-2-PG by spectrophotometry | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 16. | ALA4420397 | B | Inhibition of PGAM1 in human NCI-H1299 cells assessed as decrease in oxidative PPP flux at 20 uM by spectrophotometry | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 17. | ALA4420398 | B | Inhibition of PGAM1 in human NCI-H1299 cells assessed as decrease in NADPH/NADP+ ratio at 20 uM by spectrophotometry | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 18. | ALA4420399 | B | Inhibition of PGAM1 in human NCI-H1299 cells assessed as decrease in lipid biosynthesis at 20 uM in presence of D-[6-14C]-glucose incubated for 2 hrs by scintillation counting method | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 19. | ALA4420400 | B | Inhibition of PGAM1 in human NCI-H1299 cells assessed as decrease in RNA biosynthesis at 20 uM in presence of D-[6-14C]-glucose incubated for 2 hrs by scintillation counting method | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 20. | ALA4420426 | B | Inhibition of PGAM1 in primary leukemia cells derived from AML patient assessed as increase in 3-PG levels at 20 uM by spectrophotometry | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data |
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