# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3389934 | B | Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assay | Homo sapiens | 20 | ALA3352254 | single protein format | Scientific Literature | |
2. | ALA3389941 | B | Inhibition of recombinant HGFA (unknown origin)-mediated proteolytic activation of pro-HGF after 1 hr by immunoblotting | Homo sapiens | 3 | ALA3352254 | single protein format | Scientific Literature | |
3. | ALA3389942 | B | Inhibition of recombinant HGFA (unknown origin)-mediated proteolytic activation of pro-MSP after 1 hr by immunoblotting | Homo sapiens | 4 | ALA3352254 | single protein format | Scientific Literature | |
4. | ALA3389943 | B | Inhibition of HGFA in human MDA-MB-231 cells assessed as inhibition of c-MET phosphorylation after 15 mins by immunoblotting | Homo sapiens | 4 | ALA3352254 | cell-based format | Scientific Literature | |
5. | ALA3404294 | B | Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to cromogenic substrate addition by spectrophotometry | Homo sapiens | 12 | ALA3400148 | cell-based format | Scientific Literature | |
6. | ALA3404295 | B | Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells using Boc-QLR-AMC as substrate incubated for 30 mins prior to substrate addition by fluorescence assay | Homo sapiens | 16 | ALA3400148 | cell-based format | Scientific Literature | |
7. | ALA3404299 | B | Inhibition of HGFA (unknown origin) after 40 mins by Eadie-Hofstee plot analysis | Homo sapiens | 1 | ALA3400148 | single protein format | Scientific Literature | |
8. | ALA3404300 | B | Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells using Boc-QLR-AMC as substrate up to 20 uM incubated for 30 mins prior to substrate addition by fluorescence assay | Homo sapiens | 1 | ALA3400148 | cell-based format | Scientific Literature | |
9. | ALA3782552 | B | Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | Homo sapiens | 19 | ALA3779883 | cell-based format | Scientific Literature | |
10. | ALA4122304 | B | Inhibition of C-terminal 10-His tagged recombinant human HGFA (Gln36 to Ser655 residues) expressed in mouse Ns30 cells 1 uM after 15 mins by fluorescence assay relative to control | Homo sapiens | 3 | ALA4118144 | cell-based format | Scientific Literature | |
11. | ALA4122305 | B | Inhibition of C-terminal 10-His tagged recombinant human HGFA (Gln36 to Ser655 residues) expressed in mouse Ns30 cells 10 uM after 15 mins by fluorescence assay relative to control | Homo sapiens | 3 | ALA4118144 | cell-based format | Scientific Literature | |
12. | ALA4348027 | B | Inhibition of recombinant HGFA serine protease domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluorescence assay | Homo sapiens | 2 | ALA4346675 | single protein format | Scientific Literature | |
13. | ALA4373196 | B | Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by fluorescence assay | Homo sapiens | 21 | ALA4371074 | single protein format | Scientific Literature | |
14. | ALA4374438 | B | Inhibition of recombinant HGFA serine protease domain (unknown origin) using Boc-QLR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence based assay | Homo sapiens | 20 | ALA4373666 | single protein format | Scientific Literature | |
15. | ALA5032465 | B | Inhibition of recombinant human HGFA serine protease domain using Boc-QLR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence based assay | Homo sapiens | 18 | ALA5030567 | single protein format | Scientific Literature | |
16. | ALA5032480 | B | Inhibition of recombinant human HGFA serine protease domain mediated pro-HGF activation preincubated for 30 mins followed by pro-HGF addition and measured after 1 hr by immunoblotting analysis | Homo sapiens | 2 | ALA5030567 | single protein format | Scientific Literature |