# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3791390 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 90 to 101 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
2. | ALA3791391 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 92 to 99 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
3. | ALA3791633 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 92 to 101 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
4. | ALA3791634 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 99 to 103 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
5. | ALA3788850 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 58 to 71 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
6. | ALA3788851 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 58 to 72 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
7. | ALA3788852 | B | Binding affinity to recombinant human IL-17A assessed as increase in deuterium uptake at 103 to 114 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
8. | ALA3788853 | B | Binding affinity to recombinant human IL-17A assessed as increase in deuterium uptake at 104 to 116 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
9. | ALA3788854 | B | Binding affinity to recombinant human IL-17A assessed as increase in deuterium uptake at 100 to 116 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
10. | ALA3788855 | B | Binding affinity to recombinant human IL-17A assessed as increase in deuterium uptake at 102 to 116 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
11. | ALA3789082 | B | Binding affinity to recombinant human IL-17A assessed as increase in deuterium uptake at 102 to 120 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
12. | ALA4255293 | B | Inhibition of IL-17 (unknown origin) assessed as disruption of IL-17 protein-protein interaction | Homo sapiens | 8 | ALA4251662 | single protein format | Scientific Literature | |
13. | ALA4828401 | B | Binding affinity to human IL-17A assessed as dissociation constant in PBS-T measured after 60 mins by Biolayer interferometry | Homo sapiens | 6 | ALA4825760 | single protein format | Scientific Literature | |
14. | ALA4828402 | B | Binding affinity to human IL-17A compound pretreated with 50% human serum for 3 hrs followed by incubation with IL-17A and measured after 60 mins by pull-down assay based SDS-PAGE analysis | Homo sapiens | 1 | ALA4825760 | single protein format | Scientific Literature | |
15. | ALA4828405 | B | Binding affinity to human IL-17A compound pretreated with PBS-T for 3 hrs followed by incubation with IL-17A and measured after 60 mins by pull-down assay based SDS-PAGE analysis | Homo sapiens | 1 | ALA4825760 | single protein format | Scientific Literature | |
16. | ALA4828407 | B | Binding affinity to biotinylated human IL-17A by SPR analysis | Homo sapiens | 3 | ALA4825760 | single protein format | Scientific Literature | |
17. | ALA4828408 | B | Binding affinity to biotinylated human IL-17A assessed as inhibition of IL-17A interaction with 1L-17RA by ELISA | Homo sapiens | 2 | ALA4825760 | single protein format | Scientific Literature | |
18. | ALA4831440 | B | Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA method | Homo sapiens | 6 | ALA4828772 | cell-based format | Scientific Literature | |
19. | ALA4842297 | B | Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assay | Homo sapiens | 6 | ALA4840383 | cell-based format | Scientific Literature | |
20. | ALA5034281 | B | Inhibition of IL-17A (unknown origin) by ELISA II | Homo sapiens | 2 | ALA5033997 | single protein format | Scientific Literature |