# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3398686 | B | Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by gel-based excision activity assay | Homo sapiens | 4 | ALA3397015 | single protein format | Scientific Literature | |
2. | ALA3398689 | B | Inhibition of human purified MPG binding to immobilized ethenoadenine containing 5'-TCGAGGATCCTGAGCTCGAGTCGACGXTCGCGAATTCTGCGGATCCAAGC-3' duplex oligonucleotide at 5 to 40 uM by SPR assay | Homo sapiens | 1 | ALA3397015 | single protein format | Scientific Literature | |
3. | ALA3398690 | B | Inhibition of human purified MPG binding to immobilized ethenoadenine containing 5'-TCGAGGATCCTGAGCTCGAGTCGACGXTCGCGAATTCTGCGGATCCAAGC-3' duplex oligonucleotide at 40 uM by SPR assay | Homo sapiens | 1 | ALA3397015 | single protein format | Scientific Literature | |
4. | ALA3398693 | B | Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates at 20 uM by gel-based excision activity assay | Homo sapiens | 7 | ALA3397015 | single protein format | Scientific Literature | |
5. | ALA3398694 | B | Inhibition of MPG in human A549 cell extracts at 50 to 300 uM using 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by gel-based excision activity assay | Homo sapiens | 2 | ALA3397015 | single protein format | Scientific Literature | |
6. | ALA3398695 | B | Inhibition of MPG in human HeLa cell extracts at 50 to 300 uM using 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by gel-based excision activity assay | Homo sapiens | 2 | ALA3397015 | single protein format | Scientific Literature | |
7. | ALA3398696 | B | Inhibition of MPG in human A549 cells assessed as reduction in DNA repair at 200 and 300 uM using ethenoadenine-containing M13mp18 plasmids by plasmid based in-cell repair assay | Homo sapiens | 1 | ALA3397015 | cell-based format | Scientific Literature | |
8. | ALA3398698 | B | Inhibition of MPG in human HeLa cells assessed as reduction in DNA repair at 200 and 300 uM using ethenoadenine-containing M13mp18 plasmids by plasmid based in-cell repair assay | Homo sapiens | 1 | ALA3397015 | cell-based format | Scientific Literature | |
9. | ALA3398700 | B | Inhibition of MPG in human HeLa cells assessed as reduction in DNA repair at 300 uM using ethenoadenine-containing M13mp18 plasmids by plasmid based in-cell repair assay | Homo sapiens | 1 | ALA3397015 | cell-based format | Scientific Literature | |
10. | ALA3398701 | B | Inhibition of MPG in human A549 cells assessed as reduction in DNA repair at 300 uM using ethenoadenine-containing M13mp18 plasmids by plasmid based in-cell repair assay | Homo sapiens | 1 | ALA3397015 | cell-based format | Scientific Literature | |
11. | ALA4725793 | B | Inhibition of human AAG using HXO2/Loop01 oligonucleotide as substrate incubated for 2 hrs by colorimetric based microplate assay | Homo sapiens | 6 | ALA4725228 | single protein format | Scientific Literature |