| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3413636 | B | Inhibition of human recombinant myostatin pre-incubated with 5 uM compound for 1 hr before addition to human HepG2 cells assessed as reduction in myostatin-mediated downstream transcriptional response by myostatin-responsive (CAGA)12-luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3413637 | B | Inhibition of human recombinant myostatin pre-incubated with compound for 1 hr before addition to human HepG2 cells assessed as reduction in myostatin-mediated downstream transcriptional response by myostatin-responsive (CAGA)12-luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA3413638 | B | Inhibition of human recombinant myostatin pre-incubated with 5 uM compound for 1 hr before addition to human HepG2 cells assessed as reduction in myostatin-mediated Smad2 phosphorylation by Western blotting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3413639 | B | Inhibition of human recombinant myostatin pre-incubated with 30 uM compound for 1 hr before addition to human HepG2 cells assessed as reduction in myostatin-mediated Smad2 phosphorylation by Western blotting method | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA3413641 | B | Inhibition of human recombinant myostatin pre-incubated with 30 uM compound for 1 hr before addition to human HepG2 cells assessed as reduction in myostatin-mediated downstream transcriptional response by myostatin-responsive (CAGA)12-luciferase reporter gene assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA3413642 | B | Binding affinity to recombinant myostatin (unknown origin) by surface plasmon resonance assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA3592250 | B | Inhibition of interaction of myostatin (unknown origin)/ActRIIA-ECD complex with ALK4-ECD-Fc at 25 uM after 120 secs by competitive binding/ Blitz binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3871202 | B | Inhibition of human recombinant myostatin expressed in HEK293 cells at 10 uM after 4 hrs by SBE4 based luciferase reporter gene assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 9. | ALA3871203 | B | Inhibition of human recombinant myostatin expressed in HEK293 cells at 3 uM after 4 hrs by SBE4 based luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3871204 | B | Inhibition of human recombinant myostatin expressed in HEK293 cells after 4 hrs by SBE4 based luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4036929 | B | Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells at 3 uM after 4 hrs by dual-luciferase reporter gene assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 12. | ALA4036930 | B | Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells at 1 uM after 4 hrs by dual-luciferase reporter gene assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 13. | ALA4036931 | B | Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual-luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4036932 | B | Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells at 5 uM after 4 hrs by dual-luciferase reporter gene assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4036933 | B | Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells at 2.5 uM after 4 hrs by dual-luciferase reporter gene assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4036934 | B | Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells at 1.25 uM after 4 hrs by dual-luciferase reporter gene assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4036935 | B | Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells at 0.63 uM after 4 hrs by dual-luciferase reporter gene assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4036936 | B | Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells at 0.32 uM after 4 hrs by dual-luciferase reporter gene assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4036937 | B | Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells at 0.16 uM after 4 hrs by dual-luciferase reporter gene assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4036938 | B | Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells at <= 0.08 uM after 4 hrs by dual-luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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