# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3419346 | B | Inhibition of NaV1.7 in C57BL/6 mouse DRG neurons at -140 mV holding potential by whole-cell patch clamp assay | Mus musculus | 2 | ALA3414527 | assay format | Scientific Literature | |
2. | ALA3419347 | B | Inhibition of NaV1.7 in C57BL/6 mouse DRG neurons held at voltage yielding 20% inactivation and depolarized to -10 mV for 40 ms every 10 s by whole-cell patch clamp assay | Mus musculus | 1 | ALA3414527 | assay format | Scientific Literature | |
3. | ALA3636867 | B | Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay | Mus musculus | 27 | ALA3632552 | single protein format | Scientific Literature | |
4. | ALA3791659 | B | Inhibition of Nav1.7 in mouse DRG neurons at 10 uM relative to control | Mus musculus | 1 | ALA3784976 | single protein format | Scientific Literature | |
5. | ALA3806749 | B | Inhibition of Nav1.7 channel in mouse CAD cells by whole-cell patch clamp assay | Mus musculus | 2 | ALA3804797 | cell-based format | Scientific Literature | |
6. | ALA3865346 | B | Inhibition of 20% inactivated mouse Nav1.7 expressed in HEK293 cells assessed as inhibition of sodium current measured for 3 to 5 mins by whole cell voltage clamp method | Mus musculus | 1 | ALA3864175 | cell-based format | Scientific Literature | |
7. | ALA3865350 | B | Inhibition of 20% inactivated Nav1.7 in C57BL/6 mouse DRG neurons assessed as inhibition of sodium currents in presence of TTX by whole cell patch clamp assay | Mus musculus | 1 | ALA3864175 | assay format | Scientific Literature | |
8. | ALA4009752 | B | Inhibition of recombinant mouse Nav1.7 expressed in HEK293 cells assessed as reduction in peak inward current at -70 mV holding potential measured after 600 secs by manual patch clamp electrophysiology assay | Mus musculus | 3 | ALA4007444 | cell-based format | Scientific Literature | |
9. | ALA4009756 | B | Inhibition of Nav1.7 in C57BL/6 mouse DRG neurons assessed as reduction in native TTX-S current amplitude by manual patch clamp electrophysiology assay | Mus musculus | 1 | ALA4007444 | assay format | Scientific Literature | |
10. | ALA4012243 | B | Inhibition of mouse Nav1.7 expressed in HEK293 cells incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assay | Mus musculus | 1 | ALA4011598 | cell-based format | Scientific Literature | |
11. | ALA4012364 | B | Inhibition of mouse Nav1.7 expressed in HEK293 cells measured after 3 to 5 mins by patchXpress electrophysiology assay | Mus musculus | 1 | ALA4011607 | cell-based format | Scientific Literature | |
12. | ALA4017823 | B | Inhibition of 50% inactivated mouse Nav1.7 expressed in HEK293 cells at holding potential of -60 mV incubated for 5 mins measured at 10 secs interval by PatchXpress electrophysiology assay | Mus musculus | 2 | ALA4017458 | cell-based format | Scientific Literature | |
13. | ALA4021697 | B | Inhibition of NaV1.7 channel in mouse DRG neurons assessed as reduction of TTX-sensitive current by whole cell patch clamp assay | Mus musculus | 1 | ALA4020748 | assay format | Scientific Literature | |
14. | ALA4021715 | B | Inhibition of 50% inactivated mouse Nav1.7alpha incubated for 5 mins measured at 10 secs interval by PatchXpress automated electrophysiology method | Mus musculus | 2 | ALA4020748 | single protein format | Scientific Literature | |
15. | ALA4046483 | B | Inhibition of mouse recombinant Nav1.7 inactivated state form expressed in HEK293 cells at -60 mV holding potential by manual patch clamp electrophysiology assay | Mus musculus | 1 | ALA4043185 | cell-based format | Scientific Literature | |
16. | ALA4046485 | B | Inhibition of mouse recombinant Nav1.7 resting state form expressed in HEK293 cells at -100 mV holding potential by manual patch clamp electrophysiology assay | Mus musculus | 1 | ALA4043185 | cell-based format | Scientific Literature | |
17. | ALA4046486 | B | Inhibition of Nav1.7 in adult mouse DRG neurons assessed as inhibition of fast-inactivating TTX-sensitive sodium currents | Mus musculus | 1 | ALA4043185 | single protein format | Scientific Literature | |
18. | ALA4055954 | B | Inhibition of mouse NaV1.7 by whole cell voltage clamp method | Mus musculus | 4 | ALA4052683 | single protein format | Scientific Literature | |
19. | ALA4056902 | B | Inhibition of slow inactivated mouse NaV1.7 expressed in HEK293 cells at -20 mV holding potential after 5 mins by IonWorks electrophysiology method | Mus musculus | 1 | ALA4052739 | cell-based format | Scientific Literature | |
20. | ALA4158635 | B | Inhibition of mouse Nav1.7 expressed in HEK293 cells after 10 mins by patchxpress-based electrophysiology | Mus musculus | 1 | ALA4152382 | cell-based format | Scientific Literature |