# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1810045 | A | Cytotoxicity against mouse Shh Light2 cells assessed as cell viability at 2.5 uM | Mus musculus | 1 | ALA1806461 | cell-based format | Scientific Literature | |
2. | ALA1827520 | F | Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay | Mus musculus | 42 | ALA1821555 | cell-based format | Scientific Literature | |
3. | ALA1827533 | F | Inhibition of Shh signaling in mouse Shh-light2 cells at 10 uM by Gli-dependent firefly luciferase reporter gene assay | Mus musculus | 2 | ALA1821555 | cell-based format | Scientific Literature | |
4. | ALA1827710 | F | Inhibition of Shh signaling in mouse Shh-light2 cells at 20 uM by Gli-dependent firefly luciferase reporter gene assay | Mus musculus | 1 | ALA1821555 | cell-based format | Scientific Literature | |
5. | ALA3999031 | A | Cytotoxicity against mouse Shh Light2 cells at 20 uM after 48 hrs | Mus musculus | 3 | ALA3997801 | cell-based format | Scientific Literature | |
6. | ALA4194330 | A | Cytotoxicity against mouse Shh Light2 cells by CellTiter Glo assay | Mus musculus | 1 | ALA4190359 | cell-based format | Scientific Literature | |
7. | ALA4194331 | A | Cytotoxicity against mouse Shh Light2 cells assessed as cell viability by CellTiter Glo assay | Mus musculus | 13 | ALA4190359 | cell-based format | Scientific Literature | |
8. | ALA4432594 | F | Effect on SHH expression in mouse Shh Light2 cells at 25 to 50 uM after 24 hrs by Western blot analysis | Mus musculus | 2 | ALA4431354 | cell-based format | Scientific Literature | |
9. | ALA4432598 | A | Cytotoxicity against mouse Shh Light2 cells up to 150 uM after 40 hrs by MTT assay | Mus musculus | 3 | ALA4431354 | cell-based format | Scientific Literature | |
10. | ALA4432600 | F | Effect on Smo expression in mouse Shh Light2 cells at 75 to 100 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
11. | ALA4432601 | F | Effect on Ptch1 expression in mouse Shh Light2 cells at 75 to 100 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
12. | ALA4432602 | F | Effect on SuFu expression in mouse Shh Light2 cells at 75 to 100 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
13. | ALA4432603 | F | Effect on SHH expression in mouse Shh Light2 cells at 75 to 100 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
14. | ALA4432608 | F | Effect on SuFu expression in mouse Shh Light2 cells at 25 to 50 uM after 24 hrs by Western blot analysis | Mus musculus | 2 | ALA4431354 | cell-based format | Scientific Literature | |
15. | ALA4432610 | F | Effect on Ptch1 expression in mouse Shh Light2 cells at 25 to 50 uM after 24 hrs by Western blot analysis | Mus musculus | 2 | ALA4431354 | cell-based format | Scientific Literature | |
16. | ALA4432611 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at G0/G1 phase at 30 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 86.2%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
17. | ALA4432612 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at G2/M phase at 30 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 6.7%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
18. | ALA4432613 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at S phase at 30 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 3.6%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
19. | ALA4432614 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at subG0 phase at 30 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 3.4%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
20. | ALA4432615 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at G0/G1 phase at 100 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 86.2%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature |