| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3539253 | A | Activity of human recombinant FMO3 expressed in microsomes isolated from baculovirus infected insect BTI-TN-5B1-4 cells assessed as enzyme-mediated 3-(2,4-dimethylphenylthio)-4-(piperazin-1-yl)phenol formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+ | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3539260 | A | Activity of human recombinant FMO3 expressed in microsomes isolated from baculovirus infected insect BTI-TN-5B1-4 cells assessed as enzyme-mediated 1-(2-(2,4-dimethylphenylsulfinyl)phenyl)piperazine formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+ | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3539565 | A | Activity of human recombinant FMO3 expressed in microsomes isolated from baculovirus infected insect BTI-TN-5B1-4 cells assessed as enzyme-mediated 4-(2-(2,4-dimethylphenylthio)phenyl)piperazin-1-ol formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+ | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3539566 | A | Activity of human recombinant FMO3 expressed in microsomes isolated from baculovirus infected insect BTI-TN-5B1-4 cells assessed as enzyme-mediated 3-methyl-4-(2-(piperazin-1-yl)phenylthio)phenyl)methanol formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+ | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3539567 | A | Activity of human recombinant FMO3 expressed in microsomes isolated from baculovirus infected insect BTI-TN-5B1-4 cells assessed as enzyme-mediated 3-methyl-4-(2-(piperazin-1-yl)phenylthio)benzoic acid formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+ | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3536560 | A | Drug metabolism assessed as human recombinant FMO3-mediated ER-879123 formation in presence of dog liver cytosolic fractions and NAD+ at 50 uM after 60 mins by LC-MS/MS method | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
| 7. | ALA3531403 | A | Drug metabolism assessed as human recombinant FMO3-mediated ER-879123 formation at 10 uM after 60 mins by LC-MS/MS method in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3531404 | A | Drug metabolism assessed as human recombinant FMO3-mediated ER-879123 formation in presence NADH at 10 uM after 60 mins by LC-MS/MS method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA3529555 | A | Drug metabolism in insect microsomes assessed as FMO3 (unknown origin)-mediated nicotinamide N-oxide formation after 30 mins by HPLC analysis | Homo sapiens | 1 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!