# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA765784 | B | Percent inhibition of PEP within 30 minutes, in an ex vivo enzyme studies, using mice brain | 3 | ALA1125957 | tissue-based format | Scientific Literature | ||
2. | ALA765785 | B | Compound was evaluated for binding inhibition against Prolyl Endopeptidase (PEP). | 3 | ALA1125957 | single protein format | Scientific Literature | ||
3. | ALA765786 | B | Compound was evaluated for the enzyme kinetic data (koff) for binding inhibition against Prolyl Endopeptidase (PEP) | 3 | ALA1125957 | single protein format | Scientific Literature | ||
4. | ALA765787 | B | Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP) | 3 | ALA1125957 | single protein format | Scientific Literature | ||
5. | ALA1110122 | B | Inhibition of mouse brain POP | Mus musculus | 5 | ALA1157839 | assay format | Scientific Literature | |
6. | ALA2212398 | B | Inhibition of prolyl endopeptidase binding to FP-rhodamine in mouse brain soluble proteome at 50 uM after 30 mins by fluorescence polarization activity-based protein profiling assay relative to control | Mus musculus | 2 | ALA2203175 | tissue-based format | Scientific Literature | |
7. | ALA3241124 | B | Competitive inhibition of mouse brain prolyl oligopeptidase | Mus musculus | 1 | ALA3232996 | tissue-based format | Scientific Literature | |
8. | ALA3270190 | B | Inhibition of Perp in mouse Neuro2a cells at 3 nM after 4 hrs by ABPP-SILAC assay | Mus musculus | 3 | ALA3259629 | cell-based format | Scientific Literature | |
9. | ALA4411114 | B | Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorometric assay | Mus musculus | 13 | ALA4406920 | assay format | Scientific Literature | |
10. | ALA4411115 | B | Inhibition of mouse PREP in N2A cells co-transfected with luciferase assessed as remaining alpha-synuclein dimerization at 10 uM measured after 4 hrs by protein fragment complementation assay relative to control | Mus musculus | 7 | ALA4406920 | cell-based format | Scientific Literature | |
11. | ALA4411116 | B | Inhibition of mouse PREP in N2A cells co-transfected with luciferase assessed as reduction in alpha-synuclein dimerization at 10 uM measured after 4 hrs by protein fragment complementation assay relative to control | Mus musculus | 12 | ALA4406920 | cell-based format | Scientific Literature |