| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3375263 | B | Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay | Homo sapiens | 84 | protein complex format | Scientific Literature | ||
| 2. | ALA3375871 | B | Inhibition of human USP1/UAF1 in human HT1299 cells assessed as increase in Ub-PCNA measured after 4 hrs by Western blotting analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA3375872 | B | Inhibition of human USP1/UAF1 in human HT1299 cells assessed as increase in Ub-PCNA measured at 1 uM after 4 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3375874 | B | Inhibition of human USP1/UAF1 in human H1299 cells assessed as reduction in colony formation after 7 days | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3375875 | B | Inhibition of human USP1/UAF1 in human H1299 cells assessed as reduction in colony formation up to 25 uM after 7 days | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3412286 | B | Inhibition of USP1/UAF1 complex (unknown origin) by Ub-Rho110 assay | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 7. | ALA3412287 | B | Inhibition of USP1/UAF1 complex (unknown origin) assessed as reduction in K63-linked diUb cleavage by gel electrophoresis based orthogonal diUb cleavage assay | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 8. | ALA3412288 | B | Inhibition of USP1/UAF1 complex (unknown origin) by Ub-PCNA substrate assay | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 9. | ALA3854650 | B | Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assay | Homo sapiens | 5 | protein complex format | Scientific Literature | ||
| 10. | ALA3854651 | B | Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate preincubated for 30 mins followed by substrate addition by fluorescence-based HTS assay | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 11. | ALA3854652 | B | Inhibition of USP1/UAF1 complex in human H596 cells assessed as potentiation of cisplatin-induced cell killing by measuring cisplatin GI50 at 1:4 cisplatin to compound ratio pretreated for 48 hrs followed by addition of fresh growth medium measured after 5 to 10 days by colony forming assay (Rvb = 486 nM) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3854653 | B | Inhibition of USP1/UAF1 complex in HEK293T cells assessed as decrease in ability of DNA polymerase eta to bypass UV-induced DNA lesions after 24 hrs by strand specific PCR-based competitive replication and adduct bypass assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5251143 | B | Inhibition of USP1/UAF1 (unknown origin) using ubiquitin rhodamine 110 as substrate at 1 to 10 uM by DUBprofiler fluorometric assay | Homo sapiens | 2 | protein complex format | Scientific Literature |
The page will load shortly, Thanks for your patience!