# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2071733 | B | Inhibition of GST-Mcl-1/BH3 domain of Bim interaction at 25 uM after 1 hr by ELISA | Homo sapiens | 15 | ALA2069165 | protein format | Scientific Literature | |
2. | ALA2071734 | B | Inhibition of GST-Mcl-1/BH3 domain of Bim interaction after 1 hr by ELISA | Homo sapiens | 3 | ALA2069165 | protein format | Scientific Literature | |
3. | ALA2071735 | B | Inhibition of GST-Mcl-1/BH3 domain of Bim interaction in human MDA-MB-468 cells at 25 uM after 24 hrs by Western blotting relative to control | Homo sapiens | 3 | ALA2069165 | cell-based format | Scientific Literature | |
4. | ALA2071736 | B | Inhibition of GST-Mcl-1/BH3 domain of Bim interaction in human MDA-MB-468 cells at 50 uM after 24 hrs by Western blotting relative to control | Homo sapiens | 3 | ALA2069165 | cell-based format | Scientific Literature | |
5. | ALA3396869 | B | Inhibition of Mcl1/Bim (unknown origin) by ELISA | Homo sapiens | 33 | ALA3393015 | protein format | Scientific Literature | |
6. | ALA4721208 | B | Inhibition of Mcl1-Bim interaction in human SK-MEL-28 cells at 30 uM incubated for 24 hrs by immunoprecipitation assay | Homo sapiens | 1 | ALA4715819 | cell-based format | Scientific Literature | |
7. | ALA5035017 | B | Inhibition of MCL1/Bim interaction in human MCF7 cells assessed as disruption of MCL1/Bim complex at 10 uM measured after 24 hrs by co-immunoprecipitation based western blot analysis relative to control | Homo sapiens | 3 | ALA5034015 | cell-based format | Scientific Literature | |
8. | ALA5096348 | B | Inhibition of C-terminal His6-tagged recombinant human MCL-1 (171 to 327 residues/biotinylated Bim (51 to 76 residues) interaction incubated for 1 hrs followed by Bim addition and measured after 2 hrs by AlphaLISA assay | Homo sapiens | 1 | ALA5096144 | protein format | Scientific Literature | |
9. | ALA5113886 | B | Inhibition of Mcl-1/Bim (unknown origin) by ELISA method | Homo sapiens | 7 | ALA5113375 | protein format | Scientific Literature | |
10. | ALA5113889 | B | Inhibition of GST-tagged Mcl-1/Bim (unknown origin) incubated for 15 mins followed by Bim addition measured after 2 hrs by ELISA method | Homo sapiens | 3 | ALA5113375 | protein format | Scientific Literature | |
11. | ALA5113898 | B | Inhibition of Mcl-1/Bim (unknown origin) by fluorescence polarisation assay | Homo sapiens | 1 | ALA5113375 | protein format | Scientific Literature | |
12. | ALA5261233 | B | Inhibition of N-terminal GST-tagged human recombinant Mcl-1 expressed in Escherichia coli /human Bim measured for 60 mins by by TR-FRET based LanthaScreen Eu-Kinase binding assay | Homo sapiens | 29 | ALA5260801 | assay format | Scientific Literature |