# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3428796 | B | Inhibition of KIF5B/RET (unknown origin) autophoshorylation | Homo sapiens | 1 | ALA3425502 | protein format | Scientific Literature | |
2. | ALA3778240 | B | Inhibition of KIF5B/RET (unknown origin) expressed in mouse BA/F3 cells assessed as reduction in cell viability after 48 hrs by Cell titre glo-based luminescence assay | Homo sapiens | 35 | ALA3774350 | cell-based format | Scientific Literature | |
3. | ALA3804159 | B | Inhibition of recombinant KIF5B/RET (unknown origin) expressed in IL3 deficient BAF3 cells assessed as reduction in cell viability after 48 hrs by CellTiter-Glo assay | Homo sapiens | 42 | ALA3797122 | cell-based format | Scientific Literature | |
4. | ALA4605789 | B | Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luciferase reporter gene assay | Homo sapiens | 11 | ALA4602715 | cell-based format | Scientific Literature | |
5. | ALA4605790 | B | Inhibition of KIF5B-RET V804M mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luciferase reporter gene assay | Homo sapiens | 3 | ALA4602715 | cell-based format | Scientific Literature | |
6. | ALA4709982 | B | Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation measured after 48 hrs by MTS assay | Homo sapiens | 38 | ALA4706552 | cell-based format | Scientific Literature | |
7. | ALA4709984 | B | Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as cell survival at 2 uM measured after 48 hrs by MTS assay relative to control | Homo sapiens | 3 | ALA4706552 | cell-based format | Scientific Literature | |
8. | ALA4709993 | B | Inhibition of KIF5B-RET fusion protein (unknown origin) by radiometric assay | Homo sapiens | 2 | ALA4706552 | protein format | Scientific Literature | |
9. | ALA4710008 | B | Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in RET autophosphorylation at 50 nM measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4706552 | cell-based format | Scientific Literature | |
10. | ALA4710010 | B | Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in SHC autophosphorylation measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4706552 | cell-based format | Scientific Literature | |
11. | ALA4834259 | B | Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferation assay | Homo sapiens | 12 | ALA4831559 | cell-based format | Scientific Literature | |
12. | ALA5152026 | B | Inhibition of KIF5B-RET (unknown origin) assessed as inhibition of RET autophosphorylation expressed in mouse BaF3 cells | Homo sapiens | 1 | ALA5150004 | cell-based format | Scientific Literature |