| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3386352 | B | Inhibition of HDAC1/2/3 in human HeLa cells assessed as p21 gene expression at 3 uM after 15 hrs by luciferase reporter gene assay relative to SNDX-275 | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 2. | ALA3386353 | B | Inhibition of HDAC1/2/3 in human HeLa cells assessed as p21 gene expression at 10 uM after 15 hrs by luciferase reporter gene assay relative to SNDX-275 | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 3. | ALA3776141 | B | Inhibition of HDAC1/2/3 in human HCT116 cells assessed as upregulation of histone H3 acetylation at 10 to 1000 nM after 6 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3776322 | B | Inhibition of HDAC1/2/3 in human MV4-11 cells assessed as upregulation of histone H3 acetylation at 1000 nM after 6 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3776323 | B | Inhibition of HDAC1/2/3 in human MV4-11 cells assessed as upregulation of histone H3 acetylation at 10 to 1000 nM after 6 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3829049 | B | Inhibition of HDAC1/2/3 in human A2780S cells assessed as histone H3 acetylation incubated for 6 hrs by cytoblot assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA3829603 | B | Inhibition of HDAC1/2/3 in human MV4-11 cells assessed as upregulation of acetylated histone H3 level after 6 hrs by Western blot method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3829604 | B | Inhibition of HDAC1/2/3 in human HCT116 cells assessed as upregulation of acetylated histone H3 level after 6 hrs by Western blot method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA3829605 | B | Inhibition of HDAC1/2/3 in human MV4-11 cells assessed as upregulation of acetylated histone H3 level at 2 uM after 6 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3829606 | B | Inhibition of HDAC1/2/3 in human HCT116 cells assessed as upregulation of acetylated histone H3 level at 2 uM after 6 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3861335 | B | Inhibition of HDAC1/HDAC2/HDAC3 in human HeLa nuclear extracts using MAL as substrate after 4 hrs by UHPLC-ESI-MS/MS analysis | Homo sapiens | 3 | protein format | Scientific Literature | ||
| 12. | ALA3877439 | B | Inhibition of HDAC1/HDAC2/HDAC3 signalling in human KMS-12-BM cells assessed as increase in acetylated histone-3(Lys9/Lys14) level at 2 times antiproliferative IC50 after 16 to 48 hrs by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3877440 | B | Inhibition of HDAC1/HDAC2/HDAC3 signalling in human MOLM14 cells assessed as increase in acetylated histone-3(Lys9/Lys14) level at 2 times antiproliferative IC50 after 4 to 48 hrs by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3877443 | B | Inhibition of HDAC1/HDAC2/HDAC3 signalling in human KMS-12-BM cells assessed as increase in acetylated histone-3(Lys9/Lys14) level at 15 uM up to 48 hrs by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3877444 | B | Inhibition of HDAC1/HDAC2/HDAC3 signalling in human MOLM14 cells assessed as increase in acetylated histone-3(Lys9/Lys14) level at 15 uM up to 48 hrs by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3877451 | B | Inhibition of HDAC1/HDAC2/HDAC3 signalling in HEL 92.1.7 cells harboring JAK2 V617F mutant assessed as increase in acetylated histone-3(Lys9/Lys14) level at 0.1 to 1 uM after 1 hr by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3877452 | B | Inhibition of HDAC1/HDAC2/HDAC3 signalling in HEL 92.1.7 cells harboring JAK2 V617F mutant assessed as increase in acetylated histone-3(Lys9/Lys14) level at >1 uM after 1 hr by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3879724 | B | Inhibition of HDAC1/HDAC2/HDAC3 in human U937 cells assessed as increase in histone H3 acetylation at 2 uM after 18 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3879726 | B | Inhibition of HDAC1/HDAC2/HDAC3 in human U937 cells assessed as increase in histone H3 acetylation at 30 uM after 18 hrs by Western blot method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA4017049 | B | Inhibition of HDAC1/2/3 in human Cal27CisR cells assessed as increase in acetylation of histone H3 at 10 uM after 24 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature |
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