| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA991363 | B | Inhibition of Mycobacterium tuberculosis purified DNA gyrase | Mycobacterium tuberculosis | 1 | assay format | Scientific Literature | ||
| 2. | ALA1280244 | B | Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrB | Mycobacterium tuberculosis | 4 | protein complex format | Scientific Literature | ||
| 3. | ALA1280256 | B | Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrB assessed as concentration required for inducing cleavage | Mycobacterium tuberculosis | 2 | protein complex format | Scientific Literature | ||
| 4. | ALA2344503 | B | Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrB assessed as reduction of enzyme supercoiling activity using relaxed pBR322 DNA substrate incubated for 1 hr at 37 degC by ethidium bromide based gel electrophoresis | Mycobacterium tuberculosis | 14 | assay format | Scientific Literature | ||
| 5. | ALA3090429 | B | Inhibition of Mycobacterium tuberculosis DNA gyrase super coiling activity of relaxed pBR322 using ethidium bromide staining by agarose gel electrophoresis | Mycobacterium tuberculosis | 25 | assay format | Scientific Literature | ||
| 6. | ALA3090395 | B | Inhibition of Mycobacterium tuberculosis DNA gyrase super coiling activity of relaxed pBR322 at 25 uM using ethidium bromide staining by agarose gel electrophoresis | Mycobacterium tuberculosis | 25 | assay format | Scientific Literature | ||
| 7. | ALA3090396 | B | Inhibition of Mycobacterium tuberculosis DNA gyrase super coiling activity of relaxed pBR322 at 50 uM using ethidium bromide staining by agarose gel electrophoresis | Mycobacterium tuberculosis | 25 | assay format | Scientific Literature | ||
| 8. | ALA3117257 | B | Inhibition of Mycobacterium tuberculosis H37Rv DNA gyrase assessed as inhibition of pBR322 DNA supercoiling after 90 mins by agarose gel electrophoresis | Mycobacterium tuberculosis H37Rv | 2 | assay format | Scientific Literature | ||
| 9. | ALA3294030 | B | Inhibition of Mycobacterium tuberculosis H37Rv DNA gyrase holoenzyme-mediated supercoiling of pBR322 DNA after 90 mins by agarose gel electrophoresis | Mycobacterium tuberculosis H37Rv | 12 | assay format | Scientific Literature | ||
| 10. | ALA3294038 | B | Inhibition of Mycobacterium tuberculosis H37Rv DNA gyrase holoenzyme using pBR322 DNA as substrate assessed as linear DNA level at 0.02 to 11 uM after 60 mins by cleavable complex assay relative to control | Mycobacterium tuberculosis H37Rv | 1 | assay format | Scientific Literature | ||
| 11. | ALA3294039 | B | Inhibition of Mycobacterium tuberculosis H37Rv DNA gyrase holoenzyme using pBR322 DNA as substrate assessed as single stranded nicked DNA level at 0.02 to 11 uM after 60 mins by cleavable complex assay relative to control | Mycobacterium tuberculosis H37Rv | 1 | assay format | Scientific Literature | ||
| 12. | ALA3294040 | B | Inhibition of Mycobacterium tuberculosis H37Rv DNA gyrase holoenzyme using pBR322 DNA as substrate assessed as intact DNA level at 0.02 to 11 uM after 60 mins by cleavable complex assay relative to control | Mycobacterium tuberculosis H37Rv | 1 | assay format | Scientific Literature | ||
| 13. | ALA3292164 | B | Inhibition of Mycobacterium tuberculosis H37Rv DNA gyrase holoenzyme using pBR322 DNA as substrate assessed as increase in single-strand cleaved plasmid DNA level after 60 mins by cleavable complex assay relative to control | Mycobacterium tuberculosis H37Rv | 1 | assay format | Scientific Literature | ||
| 14. | ALA3390735 | B | Inhibition of Mycobacterium tuberculosis DNA gyrase using relaxed pBR322 as substrate after 30 mins by supercoiling assay | Mycobacterium tuberculosis | 33 | assay format | Scientific Literature | ||
| 15. | ALA3390738 | B | Binding affinity to Mycobacterium tuberculosis DNA gyrase by differential scanning fluorimetry | Mycobacterium tuberculosis | 1 | assay format | Scientific Literature | ||
| 16. | ALA3386589 | B | Inhibition of Mycobacterium tuberculosis DNA gyrase-mediated relaxed pBR322 DNA supercoiling by gel electrophoresis | Mycobacterium tuberculosis | 4 | assay format | Scientific Literature | ||
| 17. | ALA3367585 | B | Inhibition of Mycobacterium tuberculosis DNA gyrase supercoiling activity using relaxed pBR322 substrate incubated for 30 mins by ethidium bromide staining method | Mycobacterium tuberculosis | 32 | assay format | Scientific Literature | ||
| 18. | ALA3405737 | B | Inhibition of Mycobacterium tuberculosis GyrA/GyrB using relaxed pBR322 substrate incubated for 30 mins by ethidium bromide staining and electrophoresis based DNA supercoiling assay | Mycobacterium tuberculosis | 52 | assay format | Scientific Literature | ||
| 19. | ALA3610297 | B | Inhibition of Mycobacterium tuberculosis H37Rv DNA gyrase assessed as supercoiling of pBR322 DNA after 90 mins by agarose gel electrophoresis method | Mycobacterium tuberculosis H37Rv | 9 | assay format | Scientific Literature | ||
| 20. | ALA3630322 | B | Inhibition of DNA gyrase GyrA/GyrB in Mycobacterium tuberculosis incubated for 30 mins assessed as reduction in supercoiling of relaxed relaxed pBR322 DNA by ethidium bromide staining based agarose gel electrophoresis method | Mycobacterium tuberculosis | 50 | assay format | Scientific Literature |
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