# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3428924 | B | Inhibition of CCDC6/RET (unknown origin) autophoshorylation | Homo sapiens | 1 | ALA3425502 | protein format | Scientific Literature | |
2. | ALA3831014 | B | Inhibition of CCDC6-RET (unknown origin) expressed in mouse BaF3 cells assessed as inhibition of cell proliferation after 72 hrs by SRB/CCK-8 assay | Homo sapiens | 2 | ALA3826932 | cell-based format | Scientific Literature | |
3. | ALA3868195 | B | Inhibition of CCDC6/RET (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation after 72 hrs by MTT assay | Homo sapiens | 2 | ALA3867468 | cell-based format | Scientific Literature | |
4. | ALA3868197 | B | Inhibition of CCDC6/RET phosphorylation at Y905 residue (unknown origin) expressed in mouse BaF3 cells after 1 hr by Western blot analysis | Homo sapiens | 1 | ALA3867468 | cell-based format | Scientific Literature | |
5. | ALA3868198 | B | Inhibition of CCDC6/RET phosphorylation at Y905 residue (unknown origin) expressed in mouse BaF3 cells at 1 uM after 1 hr by Western blot analysis | Homo sapiens | 1 | ALA3867468 | cell-based format | Scientific Literature | |
6. | ALA3868199 | B | Inhibition of CCDC6/RET (unknown origin) expressed in mouse BaF3 cells assessed as suppression of STAT3 phosphorylation at Y703 residue after 1 hr by Western blot analysis | Homo sapiens | 1 | ALA3867468 | cell-based format | Scientific Literature | |
7. | ALA3868200 | B | Inhibition of CCDC6/RET (unknown origin) expressed in mouse BaF3 cells assessed as suppression of ERK phosphorylation after 1 hr by Western blot analysis | Homo sapiens | 1 | ALA3867468 | cell-based format | Scientific Literature | |
8. | ALA3868201 | B | Inhibition of CCDC6/RET (unknown origin) expressed in mouse BaF3 cells assessed as suppression of STAT3 phosphorylation at Y703 residue at 1 uM after 1 hr by Western blot analysis | Homo sapiens | 1 | ALA3867468 | cell-based format | Scientific Literature | |
9. | ALA3868202 | B | Inhibition of CCDC6/RET (unknown origin) expressed in mouse BaF3 cells assessed as suppression of ERK phosphorylation at 1 uM after 1 hr by Western blot analysis | Homo sapiens | 1 | ALA3867468 | cell-based format | Scientific Literature | |
10. | ALA4359489 | B | Inhibition of CCDC6/RET in human TPC1 cells assessed as reduction in RET phosphorylation at Y1062 residue at 0.3 to 30 nM measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4354879 | cell-based format | Scientific Literature | |
11. | ALA4359490 | B | Inhibition of CCDC6/RET in human LC2/ad cells assessed as reduction in RET phosphorylation at Y1062 residue at 0.3 to 30 nM measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4354879 | cell-based format | Scientific Literature | |
12. | ALA4359493 | B | Inhibition of CCDC6/RET in human TPC1 cells assessed as reduction in SHC phosphorylation at 0.3 to 30 nM measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4354879 | cell-based format | Scientific Literature | |
13. | ALA4359494 | B | Inhibition of CCDC6/RET in human LC2/ad cells assessed as reduction in SHC phosphorylation at 0.3 to 30 nM measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4354879 | cell-based format | Scientific Literature | |
14. | ALA4359497 | B | Inhibition of CCDC6/RET in human TPC1 cells assessed as reduction in MAPK phosphorylation at 0.3 to 30 nM measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4354879 | cell-based format | Scientific Literature | |
15. | ALA4359498 | B | Inhibition of CCDC6/RET in human LC2/ad cells assessed as reduction in MAPK phosphorylation at 0.3 to 30 nM measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4354879 | cell-based format | Scientific Literature | |
16. | ALA4359522 | B | Inhibition of CCDC6/RET in human TPC1 cells assessed as reduction in cell proliferation supplemented with fresh medium containing compound for every 2 to 3 days and measured during compound dosing | Homo sapiens | 1 | ALA4354879 | cell-based format | Scientific Literature | |
17. | ALA4359523 | B | Inhibition of CCDC6/RET in human LC2/ad cells assessed as reduction in cell proliferation supplemented with fresh medium containing compound for every 2 to 3 days and measured during compound dosing | Homo sapiens | 1 | ALA4354879 | cell-based format | Scientific Literature | |
18. | ALA4605827 | B | Inhibition of CCDC6/RET (unknown origin) transfected in human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter Glo assay | Homo sapiens | 7 | ALA4602715 | cell-based format | Scientific Literature | |
19. | ALA4709981 | B | Inhibition of CCDC6-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation measured after 48 hrs by MTS assay | Homo sapiens | 38 | ALA4706552 | cell-based format | Scientific Literature | |
20. | ALA4709983 | B | Inhibition of CCDC6-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as cell survival at 2 uM measured after 48 hrs by MTS assay relative to control | Homo sapiens | 3 | ALA4706552 | cell-based format | Scientific Literature |