# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3539895 | A | Drug transport in human OCT2 expressed in HEK Flp-In cells at 0.19 uM for 10 mins relative to control | Homo sapiens | 1 | ALA3526025 | cell-based format | Scientific Literature | |
2. | ALA3540193 | A | Drug transport in human OCT2 expressed in HEK Flp-In cells at 0.07 uM for 10 mins relative to control | Homo sapiens | 1 | ALA3526025 | cell-based format | Scientific Literature | |
3. | ALA3540194 | A | Drug transport in human OCT2 expressed in HEK Flp-In cells at 0.06 uM for 10 mins relative to control | Homo sapiens | 1 | ALA3526025 | cell-based format | Scientific Literature | |
4. | ALA3540196 | A | Drug transport in human OAT2 expressed in HEK Flp-In cells assessed as maximal rate of transport measured per mg of protein | Homo sapiens | 4 | ALA3526025 | cell-based format | Scientific Literature | |
5. | ALA3536920 | A | Drug uptake assessed as OCT2 (unknown origin)-mediated drug uptake expressed in HEK293 cells by liquid scintillation counting relative to control | Homo sapiens | 1 | ALA3525903 | cell-based format | Scientific Literature | |
6. | ALA3536921 | A | Drug uptake assessed as OCT2 (unknown origin)-mediated drug uptake expressed in HEK293 cells by liquid scintillation counting in presence of 10 mM cimetidine OCT inhibitor | Homo sapiens | 1 | ALA3525903 | cell-based format | Scientific Literature | |
7. | ALA3536924 | A | Inhibition of OCT2 (unknown origin) expressed in HEK293 cells assessed as reduction of [3H]MPP+ substrate uptake at 100 uM by liquid scintillation counting | Homo sapiens | 1 | ALA3525903 | cell-based format | Scientific Literature | |
8. | ALA3536925 | A | Inhibition of OCT2 (unknown origin) expressed in HEK293 cells assessed as reduction of [14C]metformin substrate uptake at 100 uM by liquid scintillation counting | Homo sapiens | 1 | ALA3525903 | cell-based format | Scientific Literature | |
9. | ALA3536926 | A | Inhibition of OCT2 (unknown origin) expressed in HEK293 cells assessed as reduction of [ethyl 1-14C]TEA substrate uptake at 100 uM by liquid scintillation counting | Homo sapiens | 1 | ALA3525903 | cell-based format | Scientific Literature | |
10. | ALA3528440 | A | Drug transport in human OAT2 expressed in HEK Flp-In cells | Homo sapiens | 4 | ALA3526025 | cell-based format | Scientific Literature | |
11. | ALA3528441 | A | Transport efficiency, ratio of maximal rate of transport to Km for drug transport in human OAT2 expressed in HEK Flp-In cells measured per mg of protein | Homo sapiens | 4 | ALA3526025 | cell-based format | Scientific Literature | |
12. | ALA3528451 | A | Drug transport in human OCT2 expressed in HEK Flp-In cells at 0.009 uM for 10 mins relative to control | Homo sapiens | 1 | ALA3526025 | cell-based format | Scientific Literature | |
13. | ALA4678468 | B | Inhibition of OCT2 (unknown origin) up to 50 uM | Homo sapiens | 1 | ALA4673340 | single protein format | Scientific Literature | |
14. | ALA4809212 | B | Inhibition of human OCT2 assessed as reduction in OCT2-mediated metformin transport at 14900 uM relative to control | Homo sapiens | 1 | ALA4808180 | single protein format | Scientific Literature | |
15. | ALA4826000 | B | Inhibition of human OCT2 assessed as reduction in intracellular probe substrate accumulation upto 100 uM by microplate scintillation counter analysis relative to control | Homo sapiens | 1 | ALA4825663 | cell-based format | Scientific Literature | |
16. | ALA4837390 | B | Inhibition of OCT2 (unknown origin) expressed in HEK293 cells | Homo sapiens | 1 | ALA4837181 | cell-based format | Scientific Literature | |
17. | ALA5119567 | B | Inhibition of OCT2 mediated (unknown origin) assessed as intracellular accumulation of ASP+ relative to control | Homo sapiens | 4 | ALA5113524 | cell-based format | Scientific Literature | |
18. | ALA5119569 | A | Substrate activity at human OCT2 overexpressed in HEK293 cells at 2.5 uM incubated for 2 mins by LC-MS/MS analysis | Homo sapiens | 7 | ALA5113524 | cell-based format | Scientific Literature | |
19. | ALA5119576 | A | Substrate activity at human OCT2 overexpressed in HEK293 cells assessed as uptake ratio incubated for 2 mins by LC-MS/MS analysis | Homo sapiens | 6 | ALA5113524 | cell-based format | Scientific Literature |