# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3537676 | A | Inhibition of human recombinant AADAC | Homo sapiens | 1 | ALA3526129 | single protein format | Scientific Literature | |
2. | ALA3537677 | A | Inhibition of AADAC in human liver microsome | Homo sapiens | 1 | ALA3526129 | assay format | Scientific Literature | |
3. | ALA3537678 | A | Activity of AADAC in human lung microsome | Homo sapiens | 1 | ALA3526129 | assay format | Scientific Literature | |
4. | ALA3537679 | A | Activity of human recombinant AADAC | Homo sapiens | 3 | ALA3526129 | single protein format | Scientific Literature | |
5. | ALA3540576 | A | Activity of AADAC in human liver microsome | Homo sapiens | 3 | ALA3526129 | assay format | Scientific Literature | |
6. | ALA3540577 | A | Activity of AADAC in human jejunum microsome | Homo sapiens | 3 | ALA3526129 | assay format | Scientific Literature | |
7. | ALA3540578 | A | Activity of AADAC in human kidney microsome | Homo sapiens | 2 | ALA3526129 | assay format | Scientific Literature | |
8. | ALA3540579 | A | Ratio Vmax to Km in human recombinant AADAC | Homo sapiens | 3 | ALA3526129 | single protein format | Scientific Literature | |
9. | ALA3540583 | A | Inhibition of AADAC in human jejunum microsome | Homo sapiens | 2 | ALA3526129 | assay format | Scientific Literature | |
10. | ALA3540584 | A | Inhibition of AADAC in human kidney microsome | Homo sapiens | 1 | ALA3526129 | assay format | Scientific Literature | |
11. | ALA3528581 | A | Drug metabolism assessed as loperamide-mediated inhibition of human recombinant AADAC-mediated compound hydrolysis expressed in SF21 cells measured as enzyme activity at 5 uM relative to control | Homo sapiens | 1 | ALA3526158 | cell-based format | Scientific Literature | |
12. | ALA3528585 | A | Drug metabolism assessed as human recombinant AADAC-mediated compound hydrolysis expressed in SF21 cells at 50 uM | Homo sapiens | 2 | ALA3526158 | cell-based format | Scientific Literature | |
13. | ALA3530410 | A | Drug metabolism assessed as human recombinant AADAC-mediated compound hydrolysis at 5 uM | Homo sapiens | 1 | ALA3526158 | single protein format | Scientific Literature | |
14. | ALA3530570 | A | Drug metabolism assessed as human recombinant AADAC-mediated compound hydrolysis at 200 uM | Homo sapiens | 1 | ALA3526158 | single protein format | Scientific Literature | |
15. | ALA3530571 | A | Drug metabolism assessed as AADAC-mediated compound hydrolysis in human liver homogenates at 5 to 200 uM | Homo sapiens | 1 | ALA3526158 | tissue-based format | Scientific Literature | |
16. | ALA3530573 | A | Drug metabolism assessed as AADAC-mediated compound hydrolysis in human liver homogenates at 5 uM | Homo sapiens | 1 | ALA3526158 | tissue-based format | Scientific Literature | |
17. | ALA3530574 | A | Drug metabolism assessed as AADAC-mediated compound hydrolysis in human liver homogenates at 50 uM | Homo sapiens | 1 | ALA3526158 | tissue-based format | Scientific Literature | |
18. | ALA3530575 | A | Drug metabolism assessed as AADAC-mediated compound hydrolysis in human liver homogenates at 200 uM | Homo sapiens | 1 | ALA3526158 | tissue-based format | Scientific Literature | |
19. | ALA3757740 | A | Prodrug activation assessed as human AADAC-mediated compound hydrolysis at 50 mM after 30 mins by HPLC analysis | Homo sapiens | 3 | ALA3751766 | single protein format | Scientific Literature | |
20. | ALA4187637 | B | Inhibition of AADAC (unknown origin) expressed in baculovirus system using CMNA substrate by fluorescence based assay | Homo sapiens | 3 | ALA4184221 | assay format | Scientific Literature |