| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA915767 | B | Inhibition of beta-naphthoflavone-induced Cyp1A in rat H4II7 cell at 50 uM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA2061909 | A | Inhibition of CYP1A at > 25 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 3. | ALA1816477 | A | Inhibition of CYP1A in human liver microsomes by LC-MS/MS analysis | Homo sapiens | 18 | microsome format | Scientific Literature | ||
| 4. | ALA1832817 | A | Inhibition of CYP1A in human liver microsomes by fluorescence assay | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 5. | ALA2065233 | A | Inhibition of CYP1A up to 25 uM | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 6. | ALA1120436 | A | Inhibition of human recombinant CYP1A at 5 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA1120443 | A | Inhibition of CYP1A in human hepatocyte at 1 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5254468 | A | Inhibition of CYP1A in human liver microsomes using probe substrate at 0.1 to 100 uM in presence of NADPH | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 9. | ALA3824678 | B | Inhibition of CYP1A in human liver microsomes assessed as reduction in ethoxyresorufin o-deethylation by fluorescence assay | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 10. | ALA4265335 | A | Inhibition of CYP1A (unknown origin) | Homo sapiens | 2 | protein format | Scientific Literature | ||
| 11. | ALA4344559 | A | Time dependent inhibition of CYP1A in human liver microsomes at 10 uM preincubated for 30 mins in presence of NADPH-generating system followed by substrate addition and measured after 10 mins by HPLC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 12. | ALA4344584 | A | Irreversible inhibition of CYP1A in human liver microsomes at 10 uM preincubated for 30 mins in presence of NADPH-generating system followed by substrate addition and measured after 10 mins by HPLC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 13. | ALA4386441 | A | Inhibition of CYP1A in human liver microsomes using phenacetin as substrate at 10 uM after 10 mins by HPLC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 14. | ALA4432846 | B | Inhibition of CYP1A in human liver microsomes | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 15. | ALA4734383 | A | Induction of CYP1A1/CYP1A2 in SEAP-induced human HepG2 cells at 1 uM preincubated for 30 mins followed by addition of substrate and measured after 30 mins by luminescence assay relative to 3-methylcollantrate | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 16. | ALA5118021 | A | Inhibition of CYP1A1/2-mediated metabolite formation in rat liver microsomes assessed as reduction in N-(1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)pentadecanamide metabolism | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 17. | ALA5234597 | A | Inhibtion of CYP1A (unknown origin) | Homo sapiens | 3 | protein format | Scientific Literature | ||
| 18. | ALA5234662 | A | Potency index, ratio of test compound IC50 to Resveratrol IC50 for inhibition of CYP1A (unknown origin) | Homo sapiens | 1 | protein format | Scientific Literature |
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