# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3394976 | B | Binding affinity to Plasmodium falciparum 3D7 AMA1 (108 to 434) expressed in Escherichia coli BL21(DE3) by SPR analysis | Plasmodium falciparum 3D7 | 2 | assay format | Scientific Literature | ||
2. | ALA3394977 | B | Binding affinity to Plasmodium falciparum 3D7 AMA1 373W insertion mutant expressed in Escherichia coli BL21(DE3) by SPR analysis | Plasmodium falciparum 3D7 | 1 | assay format | Scientific Literature | ||
3. | ALA3394978 | B | Binding affinity to Plasmodium falciparum 3D7 AMA1 F367W mutant expressed in Escherichia coli BL21(DE3) at 1 and 3 mM by SPR analysis | Plasmodium falciparum 3D7 | 1 | assay format | Scientific Literature | ||
4. | ALA3394979 | B | Binding affinity to Plasmodium falciparum 3D7 5F-Trp-tagged AMA1 F367W mutant assessed as decrease in the W367 line width at 1 and 3 mM by 19F-NMR spectroscopy in presence of R1/RON2L | Plasmodium falciparum 3D7 | 3 | single protein format | Scientific Literature | ||
5. | ALA3394980 | B | Binding affinity to Plasmodium falciparum 3D7 5F-Trp-tagged AMA1 W110F mutant assessed as downfield shifts of W110 peak by 19F-NMR spectroscopy in presence of R1/RON2L | Plasmodium falciparum 3D7 | 5 | single protein format | Scientific Literature | ||
6. | ALA3394981 | B | Binding affinity to Plasmodium falciparum 3D7 5F-Trp-tagged AMA1 F367W mutant at 1 and 3 mM by 19F-NMR spectroscopy in presence of R1/RON2L | Plasmodium falciparum 3D7 | 2 | single protein format | Scientific Literature | ||
7. | ALA3414329 | B | Binding affinity to Plasmodium falciparum AMA1 at 200 uM by surface plasmon resonance method | Plasmodium falciparum | 35 | single protein format | Scientific Literature | ||
8. | ALA3598564 | B | Binding affinity to recombinant His-tagged Plasmodium falciparum 3D7 AMA1 assessed as inhibition of interaction with biotin-tagged RON2 peptide after 30 mins by AlphaScreen assay | Plasmodium falciparum 3D7 | 3 | single protein format | Scientific Literature | ||
9. | ALA3598568 | B | Competitive binding affinity to Plasmodium falciparum 3D7 AMA1 (104 to 442) at 80 uM after 200 milisecs by CPMG binding assay in presence of R1 peptide and absence of detergent | Plasmodium falciparum 3D7 | 1 | single protein format | Scientific Literature | ||
10. | ALA3598569 | B | Competitive binding affinity to Plasmodium falciparum 3D7 AMA1 (104 to 442) at 80 uM after 200 milisecs by CPMG binding assay in presence of RON2 peptide and absence of detergent | Plasmodium falciparum 3D7 | 1 | single protein format | Scientific Literature | ||
11. | ALA3598570 | B | Competitive binding affinity to Plasmodium falciparum 3D7 AMA1 (104 to 442) at 80 uM after 200 milisecs by CPMG binding assay in presence of R1 peptide and Tween 20 | Plasmodium falciparum 3D7 | 1 | single protein format | Scientific Literature | ||
12. | ALA3598571 | B | Competitive binding affinity to Plasmodium falciparum 3D7 AMA1 (104 to 442) at 80 uM after 200 milisecs by CPMG binding assay in presence of RON2 peptide and Tween 20 | Plasmodium falciparum 3D7 | 1 | single protein format | Scientific Literature | ||
13. | ALA3598572 | B | Binding affinity to Plasmodium falciparum 3D7 AMA1 (104 to 442) up to 200 uM by SPR analysis | Plasmodium falciparum 3D7 | 2 | single protein format | Scientific Literature | ||
14. | ALA3598575 | B | Binding affinity to Plasmodium falciparum 3D7 AMA1 (104 to 442) by SPR analysis | Plasmodium falciparum 3D7 | 14 | single protein format | Scientific Literature |