| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2415162 | B | Binding affinity to Pseudomonas aeruginosa PqsD H257F mutant expressed in Escherichia coli BL21 (lambdaDE3) cells by surface plasmon resonance analysis | Pseudomonas aeruginosa | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA2415163 | B | Binding affinity to Pseudomonas aeruginosa PqsD C112A mutant expressed in Escherichia coli BL21 (lambdaDE3) cells by surface plasmon resonance analysis | Pseudomonas aeruginosa | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA2415164 | B | Binding affinity to Pseudomonas aeruginosa PqsD S317F mutant expressed in Escherichia coli BL21 (lambdaDE3) cells by surface plasmon resonance analysis | Pseudomonas aeruginosa | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA3399322 | B | Inhibition of Pseudomonas aeruginosa recombinant PqsD expressed in Escherichia coli BL21 (lambdaDE3) using ACoA/beta-ketodecanoic acid as substrate after 10 mins | Pseudomonas aeruginosa | 9 | assay format | Scientific Literature | ||
| 5. | ALA3399323 | B | Inhibition of Pseudomonas aeruginosa recombinant PqsD expressed in Escherichia coli BL21 (lambdaDE3) using ACoA/beta-ketodecanoic acid as substrate at 50 uM after 10 mins | Pseudomonas aeruginosa | 16 | assay format | Scientific Literature | ||
| 6. | ALA3399324 | B | Binding affinity to Pseudomonas aeruginosa recombinant his6-tagged PqsD expressed in Escherichia coli BL21 (lambdaDE3) at 250 to 500 uM by SPR analysis | Pseudomonas aeruginosa | 3 | assay format | Scientific Literature | ||
| 7. | ALA3399325 | B | Binding affinity to Pseudomonas aeruginosa recombinant his6-tagged PqsD expressed in Escherichia coli BL21 (lambdaDE3) using AcoA as substrate at 250 to 500 uM incubated for 40 mins prior to compound addition followed by wash out for 30 mins by SPR analysis | Pseudomonas aeruginosa | 3 | assay format | Scientific Literature | ||
| 8. | ALA3421140 | B | Inhibition of recombinant His6-tagged Pseudomonas aeruginosa PqsD expressed in Escherichia coli BL21 (deltaDE3) using anthraniloyl-CoA/beta-ketodecanoic acid as substrate assessed as HHQ formation preincubated for 10 mins followed by substrate addition by HPLC/MS-MS analysis | Pseudomonas aeruginosa | 26 | assay format | Scientific Literature | ||
| 9. | ALA3421141 | B | Inhibition of recombinant His6-tagged Pseudomonas aeruginosa PqsD expressed in Escherichia coli BL21 (deltaDE3) using anthraniloyl-CoA/beta-ketodecanoic acid as substrate assessed as HHQ formation at 50 uM preincubated for 10 mins followed by substrate addition by HPLC/MS-MS analysis relative to control | Pseudomonas aeruginosa | 3 | assay format | Scientific Literature | ||
| 10. | ALA4260319 | B | Antagonist activity at Pseudomonas aeruginosa PqsD | Pseudomonas aeruginosa | 2 | single protein format | Scientific Literature | ||
| 11. | ALA4260320 | B | Inhibition of recombinant Pseudomonas aeruginosa PqsD expressed in Escherichia coli using anthraniloyl-CoA as substrate assessed as decrease in HHQ production | Pseudomonas aeruginosa | 1 | assay format | Scientific Literature | ||
| 12. | ALA4260321 | B | Binding affinity to recombinant Pseudomonas aeruginosa PqsD at 298 K by ITC assay | Pseudomonas aeruginosa | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4260322 | B | Inhibition of Pseudomonas aeruginosa PqsD | Pseudomonas aeruginosa | 2 | single protein format | Scientific Literature | ||
| 14. | ALA4348590 | B | Inhibition of Pseudomonas aeruginosa PqsD | Pseudomonas aeruginosa | 2 | single protein format | Scientific Literature |
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