# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3385405 | B | Inhibition of HIV-1 isolate YTA48P HIV-1 gp120 | Human immunodeficiency virus 1 | 1 | ALA3351853 | single protein format | Scientific Literature | |
2. | ALA3366750 | B | Inhibition of HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells after 6 to 8 hrs by luciferase assay | Human immunodeficiency virus 1 | 21 | ALA3351900 | cell-based format | Scientific Literature | |
3. | ALA3366755 | B | Inhibition of HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells compound preincubated for 1 hr measured after 48 hrs by prime/wash assay | Human immunodeficiency virus 1 | 4 | ALA3351900 | cell-based format | Scientific Literature | |
4. | ALA3366756 | B | Inhibition of HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells compound preincubated for 1 hr followed by wash out measured after 48 hrs by prime/wash assay | Human immunodeficiency virus 1 | 4 | ALA3351900 | cell-based format | Scientific Literature | |
5. | ALA3366757 | B | Ratio of EC50 for HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells with wash out to EC50 for HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells | Human immunodeficiency virus 1 | 4 | ALA3351900 | cell-based format | Scientific Literature | |
6. | ALA3366758 | B | Inhibition of HIV1 gp41 NHR assessed as inhibition of 6HB formation by FRET assay | Human immunodeficiency virus 1 | 8 | ALA3351900 | single protein format | Scientific Literature | |
7. | ALA3366759 | B | Inhibition of HIV1 gp41 NHR assessed as inhibition of 6HB formation after 30 mins by size-exclusion HPLC analysis | Human immunodeficiency virus 1 | 2 | ALA3351900 | single protein format | Scientific Literature | |
8. | ALA3412776 | B | Binding affinity to HIV1 gp41 (46 residues) by surface plasmon resonance method | Human immunodeficiency virus 1 | 3 | ALA3407456 | single protein format | Scientific Literature | |
9. | ALA3412777 | B | Binding affinity to HIV1 gp41 (46 residues) assessed as effect on protein secondary structure measured as alpha-helicity in PBS buffer at pH 7.2 by circular dichroism assay (Rvb = 117 %) | Human immunodeficiency virus 1 | 3 | ALA3407456 | single protein format | Scientific Literature |