# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4376169 | B | Binding affinity to recombinant human Frizzled-7 (Gln33 to Leu185 residues)/human IgG1 chimeric protein expressed in CHO cells assessed as association rate constant by SPR assay | Homo sapiens | 36 | ALA4373723 | cell-based format | Scientific Literature | |
2. | ALA4376170 | B | Binding affinity to recombinant human Frizzled-7 (Gln33 to Leu185 residues)/human IgG1 chimeric protein expressed in CHO cells assessed as dissociation rate constant by SPR assay | Homo sapiens | 36 | ALA4373723 | cell-based format | Scientific Literature | |
3. | ALA4376171 | B | Binding affinity to recombinant human Frizzled-7 (Gln33 to Leu185 residues)/human IgG1 chimeric protein expressed in CHO cells by SPR assay | Homo sapiens | 36 | ALA4373723 | cell-based format | Scientific Literature | |
4. | ALA4376179 | B | Inhibition of Frizzled-7 in HEK293 cells expressing Wnt assessed as reduction in Wnt signaling by firefly luciferase reporter gene assay | Homo sapiens | 5 | ALA4373723 | cell-based format | Scientific Literature | |
5. | ALA4376186 | B | Binding affinity to recombinant human Frizzled-7 (Gln33 to Leu185 residues)/human IgG1 chimeric protein expressed in CHO cells assessed as reduction in interaction of TcdB with FZD7 incubated for 1 hr by competition ELISA | Homo sapiens | 4 | ALA4373723 | cell-based format | Scientific Literature | |
6. | ALA4376188 | B | Binding affinity to recombinant human Frizzled-7 (Gln33 to Leu185 residues)/human IgG1 chimeric protein expressed in CHO cells assessed as reduction in interaction of TcdB with FZD7 by SPR | Homo sapiens | 1 | ALA4373723 | cell-based format | Scientific Literature | |
7. | ALA4404568 | B | Binding affinity to immobilized human Frizzled-7 CRD (Q33 to G173 resideus) transfected with pDisplay_BirA-ER plasmid in HEK293T cells for biotinylation by surface plasmon resonance assay | Homo sapiens | 1 | ALA4402568 | cell-based format | Scientific Literature |