# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4346437 | F | Antagonist activity at recombinant human TAS2R50 transiently expressed in HEK293T co-expressing Galpha16gust44 assessed as inhibition of andrographolide-induced intracellular calcium level by measuring remaining activity at 25 uM by fluo-4AM dye based FLIPR assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA4419024 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R50 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4419047 | F | Antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R50 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-induced increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4419212 | F | Agonist activity at human TAS2R50 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4419237 | F | Agonist activity at human TAS2R50 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level at 20 mM by Calcium-3 dye based fluorescence assay relative to control | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4421761 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R50 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
7. | ALA4421780 | F | Activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R50 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on andrographolide-induced intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data |