| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3791559 | B | Binding affinity to recombinant mouse poly His-tagged Keap1 expressed in Escherichia coli assessed as chemical modification of Cys-273 residue incubated up to 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | assay format | Scientific Literature | ||
| 2. | ALA3791560 | B | Binding affinity to recombinant mouse poly His-tagged Keap1 expressed in Escherichia coli assessed as chemical modification of Cys-489 residue incubated up to 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | assay format | Scientific Literature | ||
| 3. | ALA3788985 | B | Binding affinity to recombinant mouse poly His-tagged Keap1 expressed in Escherichia coli assessed as chemical modification of Cys-257 residue incubated up to 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | assay format | Scientific Literature | ||
| 4. | ALA3788990 | B | Binding affinity to recombinant mouse poly His-tagged Keap1 expressed in Escherichia coli assessed as chemical modification of Cys-288 residue incubated up to 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | assay format | Scientific Literature | ||
| 5. | ALA3788991 | B | Binding affinity to recombinant mouse poly His-tagged Keap1 expressed in Escherichia coli assessed as chemical modification of Cys-434 residue incubated up to 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | assay format | Scientific Literature | ||
| 6. | ALA3788992 | B | Binding affinity to recombinant mouse poly His-tagged Keap1 expressed in Escherichia coli assessed as chemical modification of Cys-613 residue incubated up to 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | assay format | Scientific Literature | ||
| 7. | ALA3788993 | B | Binding affinity to mouse V5-tagged Keap1 expressed in HEK293T cells assessed as chemical modification of Cys-257 residue at 100 uM incubated for by LC-MS/MS analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3788994 | B | Binding affinity to mouse V5-tagged Keap1 expressed in HEK293T cells assessed as chemical modification of Cys-288 residue at 100 uM incubated for by LC-MS/MS analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3788995 | B | Binding affinity to mouse V5-tagged Keap1 expressed in HEK293T cells assessed as chemical modification of Cys-489 residue at 100 uM incubated for by LC-MS/MS analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3788996 | B | Binding affinity to mouse V5-tagged Keap1 expressed in HEK293T cells assessed as chemical modification of Cys-273 residue at 100 uM incubated for by LC-MS/MS analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3788997 | B | Binding affinity to mouse V5-tagged Keap1 expressed in HEK293T cells assessed as chemical modification of Cys-434 residue at 100 uM incubated for by LC-MS/MS analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3864473 | B | Binding affinity to mouse Keap1 Kelch domain expressed in Escherichia coli BL21 by VP-ITC assay | Mus musculus | 1 | assay format | Scientific Literature | ||
| 13. | ALA4198415 | B | Binding affinity to Keap1 in NRF2+/+ MEF assessed as induction of NRF2/ARE activation-mediated HO1 expression at 10 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4198416 | B | Binding affinity to Keap1 in NRF2-/- MEF assessed as induction of HO1 expression at 10 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4198417 | B | Binding affinity to Keap1 in NRF2+/+ MEF assessed as induction of NRF2/ARE activation-mediated HO1 expression at 10 uM up to 8 hrs by RT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4198418 | B | Binding affinity to Keap1 in NRF2-/- MEF assessed as induction of NRF2/ARE activation-mediated HO1 expression at 10 uM up to 8 hrs by RT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4376065 | B | Binding affinity to Keap1 in mouse Hepa1c1c7 cells assessed as reduction in Keap1 interaction by measuring induction of NQO1 activity at 1 to 10 uM measured after 24 hrs | Mus musculus | 10 | cell-based format | Scientific Literature | ||
| 18. | ALA4376066 | B | Binding affinity to Keap1 in mouse Hepa1c1c7 cells assessed as reduction in Keap1 interaction by measuring induction of NQO1 activity measured after 24 hrs | Mus musculus | 9 | cell-based format | Scientific Literature | ||
| 19. | ALA4376079 | B | Binding affinity to Keap1 in mouse Hepa1c1c7 cells assessed as reduction in Keap1 interaction by measuring induction of NQO1 activity at 10 uM measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4376082 | B | Binding affinity to Keap1 in mouse Hepa1c1c7 cells assessed as reduction in Keap1 interaction by measuring induction of NQO1 activity at 10 uM in 1.4% DMSO measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature |
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