#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3579721	Binding	Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay	Homo sapiens	52	ALA3576865	cell-based format	Scientific Literature
2.	ALA4807192	Functional	Inverse agonist activity at human GPR174 expressed in cells assessed as inhibition of CRE-luc reporter activity by measuring decrease in Gs-protein signalling activity relative to control	Homo sapiens	50	ALA4806960	cell-based format	Patent Bioactivity Data
3.	ALA4807193	Functional	Inhibition of GPR174 (unknown origin) in cells assessed as incorporation of nuclear localization sequence into transmembrane protein by cellular redistribution assay	Homo sapiens	26	ALA4806960	assay format	Patent Bioactivity Data
4.	ALA4807194	Functional	Inverse agonist activity at human GPR174 expressed in cells assessed as inhibition of CRE-luc reporter activity by measuring decrease in Gs-protein signalling activity	Homo sapiens	50	ALA4806960	cell-based format	Patent Bioactivity Data
5.	ALA4807195	Functional	Inhibition of GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IFNgamma level measured after 2 days by ELISA	Homo sapiens	1	ALA4806960	tissue-based format	Patent Bioactivity Data
6.	ALA4807196	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IL-2 level measured after 2 days by ELISA	Homo sapiens	2	ALA4806960	tissue-based format	Patent Bioactivity Data
7.	ALA4807197	Functional	Antagonist activity at human GPR174 expressed in cells assessed as inhibition of CRE-luc reporter activity by measuring decrease in Gs-protein signalling activity relative to control	Homo sapiens	7	ALA4806960	cell-based format	Patent Bioactivity Data
8.	ALA4807198	Functional	Allosteric modulator activity at human GPR174 expressed in cells assessed as inhibition of CRE-luc reporter activity by measuring decrease in Gs-protein signalling activity relative to control	Homo sapiens	6	ALA4806960	cell-based format	Patent Bioactivity Data
9.	ALA4807199	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in natural Treg cells (FoxP3+Helios-) at 100 uM measure after 7 days by flow cytometry	Homo sapiens	1	ALA4806960	cell-based format	Patent Bioactivity Data
10.	ALA4807200	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as reduction in natural Treg cells (FoxP3+Helios+) at 100 uM measure after 7 days by flow cytometry	Homo sapiens	1	ALA4806960	cell-based format	Patent Bioactivity Data
11.	ALA4807201	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as reduction in natural Treg cells (FoxP3+Helios+) measure after 7 days by ELISA	Homo sapiens	1	ALA4806960	cell-based format	Patent Bioactivity Data
12.	ALA4807203	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IL-2 production measured after 2 days	Homo sapiens	1	ALA4806960	tissue-based format	Patent Bioactivity Data
13.	ALA4807204	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IL-6 production at 10 uM measured after 2 days relative to control	Homo sapiens	1	ALA4806960	tissue-based format	Patent Bioactivity Data
14.	ALA4807205	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IL-10 production at 10 uM measured after 2 days relative to control	Homo sapiens	1	ALA4806960	tissue-based format	Patent Bioactivity Data
15.	ALA4807206	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IFNgamma production at 10 uM measured after 2 days relative to control	Homo sapiens	1	ALA4806960	tissue-based format	Patent Bioactivity Data
16.	ALA4807207	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in TNFalpha production at 10 uM measured after 2 days relative to control	Homo sapiens	1	ALA4806960	tissue-based format	Patent Bioactivity Data
17.	ALA4807208	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as CD4+ cell population at 10 uM measured after 2 days relative to control	Homo sapiens	1	ALA4806960	tissue-based format	Patent Bioactivity Data
18.	ALA4807209	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as CD8+ cell population at 10 uM measured after 2 days relative to control	Homo sapiens	1	ALA4806960	tissue-based format	Patent Bioactivity Data
19.	ALA4807210	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as non-T cell cell population at 10 uM measured after 2 days relative to control	Homo sapiens	1	ALA4806960	tissue-based format	Patent Bioactivity Data
20.	ALA4807211	Functional	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human regulatory T cells assessed as reduction in CTLA4 expression relative to control	Homo sapiens	1	ALA4806960	tissue-based format	Patent Bioactivity Data