| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3579738 | B | Inhibition of ASIC1a in Wistar rat hippocampal neurons assessed as ASIC1a-like currents level at 10 uM by patch clamp assay | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 2. | ALA3579926 | B | Inhibition of ASIC1a in Wistar rat pyramidal hippocampal neurons assessed as ASIC1a-like currents level at 100 nM by patch clamp assay | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 3. | ALA3579927 | B | Inhibition of ASIC1a in Wistar rat pyramidal hippocampal neurons assessed as reduction in main ionic currents at 1 uM by patch clamp assay | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 4. | ALA4031235 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of peak current amplitude at 1 mM at pH 6.7 at -40 mV holding potential by two electrode voltage clamp relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4031236 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of peak current amplitude at 1 mM pretreated for 30 secs followed by pH 6.7 activation at -40 mV holding potential by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4031237 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of peak current amplitude at 300 uM co-treated at pH 6.7 activation at -40 mV holding potential by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4031238 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of peak current amplitude at 300 uM at membrane potential -60 mV by two electrode voltage clamp | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4031239 | B | Effect on rate of current decay in rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as time constant for desensitization of proton gated current at 400 uM at -40 mV holding potential by two electrode voltage clamp (Rvb = 3.5 +/- 0.3 sec) | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4031240 | B | Induction of rat ASIC1a receptor desensitization expressed in xenopus lavies oocytes assessed as delay in recovery from desensitization of proton gated current at 400 uM at -40 mV holding potential by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4031241 | B | Induction of rat ASIC1a receptor steady state desensitization expressed in xenopus lavies oocytes assessed as acidic shift in proton concentration response for activation at 400 uM at -40 mV holding potential by two electrode voltage clamp (Rvb = 6.81 +/- 0.01 No_unit) | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4031242 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at pH 6.9 by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4031243 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at pH 6.7 by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4031244 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at pH 6.4 by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4031245 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at less than pH 4.5 by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4031246 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes up to 10 mM at greater than pH 5 by two electrode voltage clamp | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 16. | ALA4031247 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at 0.1 to 3 mM at greater than pH 5 by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4031248 | B | Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at 0.03 to 3 mM at greater than pH 5 by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4031249 | B | Inhibition of rat ASIC1a receptor R190Q/D237N double mutant expressed in xenopus lavies oocytes at pH 4.8 by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4031252 | B | Inhibition of rat ASIC1a receptor R64A mutant expressed in xenopus lavies oocytes up to 3 mM at pH 4 to 5 by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4031253 | B | Inhibition of rat ASIC1a receptor K76A mutant expressed in xenopus lavies oocytes up to 3 mM at pH 4 to 5 by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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