# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA706222 | B | Inhibitory concentration against lysyl oxidase | 1 | single protein format | Scientific Literature | |||
2. | ALA829079 | B | Inhibition of protein-bound lysine binding to Lysyl oxidase of porcine aorta | Sus scrofa | 4 | tissue-based format | Scientific Literature | ||
3. | ALA3997547 | B | Inhibition of full length recombinant human LOX expressed in HEK cells assessed as reduction in H2O2 production using DAP as substrate preincubated for 2 hrs followed by substrate addition measured every 2 minutes for 50 minutes in presence of BSA by Amplex red dye based fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA4052333 | B | Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs followed by substrate addition in presence of 0.1% BSA measured every 2 mins for 1 hr by amplex red reagent-based fluorescence assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
5. | ALA4235819 | B | Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr by fluorimetric method | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
6. | ALA4235823 | B | Inhibition of recombinant human LOX expressed in HEK293 cells at 10 uM using diaminopentane as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr by fluorimetric method relative to control | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
7. | ALA4323284 | B | Inhibition of LOX in human IMR90 cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4421177 | B | Inhibition of LOX in human MDA-MB-231 cells assessed as reduction in EGF-stimulated AKT phosphorylation at 20 uM by ELISA relative to control | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
9. | ALA4421203 | B | Inhibition of LOX in EGF-stimulated human MDA-MB-231 cells assessed as reduction of surface EGFR expression at 20 uM by Western blot analysis | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
10. | ALA4421207 | B | Inhibition of LOX in human MDA-MB-231 cells assessed as reduction of MATN2 expression at 20 uM by Western blot analysis | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
11. | ALA4421208 | B | Inhibition of LOX in human MDA-MB-231 cells assessed as reduction of reduction of MATN2 expression at 1 mM by Western blot analysis | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
12. | ALA4421209 | B | Inhibition of LOX in human MDA-MB-231 cells assessed as increase in SMAD2 phosphorylation by Western blot analysis | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data |