# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3587395 | Binding | Inhibition of Wistar rat EDL muscle SERCA1a after 1 hr | Rattus norvegicus | 1 | ALA3585273 | single protein format | Scientific Literature | |
2. | ALA4612466 | Binding | Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Rattus norvegicus | 7 | ALA4610111 | cell-based format | Scientific Literature | |
3. | ALA4612470 | Binding | Inhibition of SERCA1 in glucose-stimulated rat INS-1E cells assessed as decline in insulin release preincubated for 24 hrs followed by glucose addition and measured after 30 mins by RIA | Rattus norvegicus | 7 | ALA4610111 | assay format | Scientific Literature | |
4. | ALA4612471 | Binding | Inhibition of SERCA1 in rat INS-1E cells assessed as induction of apoptosis by measuring decrease in living cells at IC50 for cell viability incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Rattus norvegicus | 7 | ALA4610111 | cell-based format | Scientific Literature | |
5. | ALA4612472 | Binding | Inhibition of SERCA1 in rat INS-1E cells assessed as induction of apoptosis by measuring increase in early apoptotic cells at IC50 for cell viability incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Rattus norvegicus | 7 | ALA4610111 | cell-based format | Scientific Literature | |
6. | ALA4612473 | Binding | Inhibition of SERCA1 in rat INS-1E cells assessed as induction of apoptosis by measuring increase in late apoptotic cells at IC50 for cell viability incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Rattus norvegicus | 7 | ALA4610111 | cell-based format | Scientific Literature | |
7. | ALA4612474 | Binding | Inhibition of SERCA1 in rat INS-1E cells assessed as insulin release preincubated for 24 hrs followed by incubation in glucose-free buffer and measured after 30 mins by RIA | Rattus norvegicus | 7 | ALA4610111 | cell-based format | Scientific Literature |