| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3592414 | B | Inhibition of ASH1L (unknown origin) at 1 uM after 1 hr by filter-based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA3773106 | B | Binding affinity to biotinylated ASH1L bromodomain (unknown origin) expressed in Escherichia coli at 0.2 to 1 uM by Biolayer Interferometric analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 3. | ALA3784079 | B | Inhibition of human ASH1L at 10 and 50 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA3782787 | B | Binding affinity to human His6-tagged ASH1L (E2433 to E2564 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 5. | ALA3821912 | B | Inhibition of ASH1L (unknown origin) at 1 to 50 uM by TCA precipitation assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA3859052 | B | Inhibition of ASH1L (unknown origin) at 50 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4005631 | B | Inhibition of ASH1L (unknown origin) at 10 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by Topcount method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4005660 | B | Inhibition of ASH1L (unknown origin) at 1 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by Topcount method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4051543 | B | Inhibition of ASH1L (unknown origin) assessed as change in melting temperature at 10 uM by SYPRO Orange-dye based fluorescence thermal shift assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4154885 | B | Binding affinity to His6-tagged human ASH1L (E2433 to E2564 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 11. | ALA4346641 | B | Inhibition of ASH1L (unknown origin) at 10 uM using [3H-SAM] and nucleosome as substrate incubated for 1 hr by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4377330 | B | Inhibition of human ASH1L up to 50 uM using chicken nucleosome as substrate and in presence of [3H]-SAM incubated for 1 hr by filter-based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4416350 | A | Inhibition of human ASH1L expressed in Escherichia coli assessed as reduction in methylated polynucleosome level using polynucleosome as substrate in presence of [3H] SAM incubated for 15 mins by scintillation counting | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA4480242 | B | Inhibition of ASH1L (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | single protein format | Scientific Literature | ||
| 15. | ALA4482797 | B | Inhibition of MOCR-fused ASH1L SET-BAH ( 2069 to 2833 amino acids) (unknown origin) expressed as in Escherichia coli BL21 (DE3) T1R cells using SAM and chicken mono/dinucleosomes incubated for 1 hr by scintillation counting assay | Homo sapiens | 312 | assay format | Patent Bioactivity Data | ||
| 16. | ALA4482798 | B | Binding affinity to MOCR-fused ASH1L SET-BAH ( 2069 to 2833 amino acids) (unknown origin) expressed as in Escherichia coli BL21 (DE3) T1R cells at 0.1 mM by isothermal titration calorimetry | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
| 17. | ALA4650041 | B | Thermal Shift Assay. Domain start/stop: E2433-E2559 | Homo sapiens | 14 | single protein format | EUbOPEN Chemogenomic Library | ||
| 18. | ALA4767058 | B | Binding affinity to human recombinant His6-tagged ASH1L (E2433 to E2564 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as change in melting temperature at 200 uM incubated for 30 mins by SYPRO orange dye based thermal shift assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 19. | ALA5030817 | B | Inhibition of ASH1L (unknown origin) at 1 to 10 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 20. | ALA5052930 | B | Inhibition of ASH1L SET-BAH construct (unknown origin) (2069 to 2833 residues) using SAM as substrate incubated for 1 hr and measured after 45 mins by Beckman scintillation counter method | Homo sapiens | 64 | single protein format | Patent Bioactivity Data |
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